open access

Vol 50, No 3 (2018)
Original and clinical articles
Published online: 2018-07-16
Submitted: 2017-04-01
Accepted: 2018-05-08
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The assessment of platelet function using multiple electrode aggregometry in practical procedures in anaesthesia

Jan Pluta, Barbara Nicińska, Michał Ciurzyński, Janusz Trzebicki
DOI: 10.5603/AIT.a2018.0025
·
Pubmed: 30011057
·
Anaesthesiol Intensive Ther 2018;50(3):210-214.

open access

Vol 50, No 3 (2018)
Original and clinical articles
Published online: 2018-07-16
Submitted: 2017-04-01
Accepted: 2018-05-08

Abstract

Background: Platelets are responsible for primary haemostasis. Patients with suspected platelet dysfunction require prompt clinical assessment when qualifying for emergency surgical procedures. The purpose of this article is to present our experience in platelet function assessment using whole-blood multiple electrode aggregometry (MEA) in various clinical conditions. Case reports: Retrospective analysis of three patients with thrombocytopathy associated with normal platelet counts was performed using standard laboratory tests complemented by MEA. In two cases, platelet dysfunction was due to antiplatelet drugs, while in one other case it was caused by chronic kidney disease. Conclusions: Anaesthesiologists strive to make the perioperative period as safe as possible. Platelet function assessment should be considered in every patient in whom haemostatic disturbances are suspected. MEA provides support for clinical decision-making, especially in patients who undergo haemodialysis or require antiplatelet therapy, and are in need of emergency surgery.

Abstract

Background: Platelets are responsible for primary haemostasis. Patients with suspected platelet dysfunction require prompt clinical assessment when qualifying for emergency surgical procedures. The purpose of this article is to present our experience in platelet function assessment using whole-blood multiple electrode aggregometry (MEA) in various clinical conditions. Case reports: Retrospective analysis of three patients with thrombocytopathy associated with normal platelet counts was performed using standard laboratory tests complemented by MEA. In two cases, platelet dysfunction was due to antiplatelet drugs, while in one other case it was caused by chronic kidney disease. Conclusions: Anaesthesiologists strive to make the perioperative period as safe as possible. Platelet function assessment should be considered in every patient in whom haemostatic disturbances are suspected. MEA provides support for clinical decision-making, especially in patients who undergo haemodialysis or require antiplatelet therapy, and are in need of emergency surgery.
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Keywords

haemostasis; thrombocytes, function; thrombocyte activation, aggregation; monitoring, point-of-care; multiple electrode aggregometry; thromboelastometry

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About this article
Title

The assessment of platelet function using multiple electrode aggregometry in practical procedures in anaesthesia

Journal

Anaesthesiology Intensive Therapy

Issue

Vol 50, No 3 (2018)

Pages

210-214

Published online

2018-07-16

DOI

10.5603/AIT.a2018.0025

Pubmed

30011057

Bibliographic record

Anaesthesiol Intensive Ther 2018;50(3):210-214.

Keywords

haemostasis
thrombocytes
function
thrombocyte activation
aggregation
monitoring
point-of-care
multiple electrode aggregometry
thromboelastometry

Authors

Jan Pluta
Barbara Nicińska
Michał Ciurzyński
Janusz Trzebicki

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