open access

Vol 44, No 1 (2012 Jan-Mar)
Case reports
Published online: 2012-03-30
Submitted: 2012-03-30
Accepted: 2012-03-30
Get Citation

Neuromuscular block reversal with sugammadex in a morbidly obese patient with myasthenia gravis

Jakub Jakubiak, Tomasz Gaszyński, Wojciech Gaszyński
Anaesthesiol Intensive Ther 2012;44(1):28-30.

open access

Vol 44, No 1 (2012 Jan-Mar)
Case reports
Published online: 2012-03-30
Submitted: 2012-03-30
Accepted: 2012-03-30

Abstract

BACKGRAOUND: Myasthenia gravis is a rare immunological illness that impairs neuromuscular transmission. Myasthenic patients are usually hypersensitive to non-depolarising muscle relaxants, and reversal with neostigmine is rarely effective. We report the successful reversal of rocuroniuminduced neuromuscular block in a morbidly obese myasthenic patient.

CASE REPORT: A 38-year-old morbidly obese (body weight 160 kg, BMI 48.8 kg m-2) woman was scheduled for elective laparoscopic gastric banding. She was anaesthetised with propofol-based TIVA; intubation was facilitated by 24 mg of rocuronium. After spontaneous recovery of T1, she received 200 mg of sugammadex, which completely restored the NMT ratio (TOF=100%) within 2 min and 48 sec., and she was extubated. No postoperative complications were observed.

CONCLUSION: Sugammadex can be successfully used in myasthenic patients, allowing for the safe use of muscle relaxants in these patients.

Abstract

BACKGRAOUND: Myasthenia gravis is a rare immunological illness that impairs neuromuscular transmission. Myasthenic patients are usually hypersensitive to non-depolarising muscle relaxants, and reversal with neostigmine is rarely effective. We report the successful reversal of rocuroniuminduced neuromuscular block in a morbidly obese myasthenic patient.

CASE REPORT: A 38-year-old morbidly obese (body weight 160 kg, BMI 48.8 kg m-2) woman was scheduled for elective laparoscopic gastric banding. She was anaesthetised with propofol-based TIVA; intubation was facilitated by 24 mg of rocuronium. After spontaneous recovery of T1, she received 200 mg of sugammadex, which completely restored the NMT ratio (TOF=100%) within 2 min and 48 sec., and she was extubated. No postoperative complications were observed.

CONCLUSION: Sugammadex can be successfully used in myasthenic patients, allowing for the safe use of muscle relaxants in these patients.

Get Citation

Keywords

neuromuscular relaxants, antagonists, sugammadex; neuromuscular diseases, myasthenia gravis; surgery, bariatric

About this article
Title

Neuromuscular block reversal with sugammadex in a morbidly obese patient with myasthenia gravis

Journal

Anaesthesiology Intensive Therapy

Issue

Vol 44, No 1 (2012 Jan-Mar)

Pages

28-30

Published online

2012-03-30

Bibliographic record

Anaesthesiol Intensive Ther 2012;44(1):28-30.

Keywords

neuromuscular relaxants
antagonists
sugammadex
neuromuscular diseases
myasthenia gravis
surgery
bariatric

Authors

Jakub Jakubiak
Tomasz Gaszyński
Wojciech Gaszyński

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

VM Media sp. z o.o. VM Group sp.k., Grupa Via Medica, Świętokrzyska 73 St., 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl