open access

Vol 87, No 5 (2019)
CASE REPORTS
Published online: 2019-10-31
Submitted: 2019-06-17
Accepted: 2019-09-02
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Oligo-recurrence from anaplastic lymphoma kinase-rearranged lung adenocarcinoma

Yuika Sasatani, Shinichiro Okauchi, Gen Ohara, Katsunori Kagohashi, Kesato Iguchi, Koji Kawai, Hiroaki Satoh
DOI: 10.5603/ARM.2019.0053
·
Pubmed: 31680231
·
Adv Respir Med 2019;87(5):301-304.

open access

Vol 87, No 5 (2019)
CASE REPORTS
Published online: 2019-10-31
Submitted: 2019-06-17
Accepted: 2019-09-02

Abstract

Anaplastic lymphoma kinase rearranged non-small-cell lung cancer is a rare disease. Among them, a subset of patients exist who exhibit relatively slowly progressing symptoms and have oligo-metastases. In this article, we present two cases of ALK rearran-ged lung adenocarcinoma in patients who experienced postoperative oligo-recurrence. Both cases were treated with surgical resection and gamma knife irradiation for oligo-recurrence. After local therapy, the first patient remained disease free for over  23 months; the second for over 18 months. It appears that some patients with ALK rearranged NSCLC experience oligo-recurrence in their clinical course. For such patients, appropriate local therapy may be beneficial in improving both the quality of life and the prognosis.

Abstract

Anaplastic lymphoma kinase rearranged non-small-cell lung cancer is a rare disease. Among them, a subset of patients exist who exhibit relatively slowly progressing symptoms and have oligo-metastases. In this article, we present two cases of ALK rearran-ged lung adenocarcinoma in patients who experienced postoperative oligo-recurrence. Both cases were treated with surgical resection and gamma knife irradiation for oligo-recurrence. After local therapy, the first patient remained disease free for over  23 months; the second for over 18 months. It appears that some patients with ALK rearranged NSCLC experience oligo-recurrence in their clinical course. For such patients, appropriate local therapy may be beneficial in improving both the quality of life and the prognosis.

Get Citation

Keywords

oligo-recurrence, local therapy, ALK rearrangement

About this article
Title

Oligo-recurrence from anaplastic lymphoma kinase-rearranged lung adenocarcinoma

Journal

Advances in Respiratory Medicine

Issue

Vol 87, No 5 (2019)

Pages

301-304

Published online

2019-10-31

DOI

10.5603/ARM.2019.0053

Pubmed

31680231

Bibliographic record

Adv Respir Med 2019;87(5):301-304.

Keywords

oligo-recurrence
local therapy
ALK rearrangement

Authors

Yuika Sasatani
Shinichiro Okauchi
Gen Ohara
Katsunori Kagohashi
Kesato Iguchi
Koji Kawai
Hiroaki Satoh

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