open access

Vol 87, No 4 (2019)
Review paper
Published online: 2019-08-30
Submitted: 2019-02-14
Accepted: 2019-07-16
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Disseminated Bacille Calmette-Guérin infection at a glance: a mini review of the literature

Maryam Hassanzad, Ali Valinejadi, Sepideh Darougar, Seyed Karen Hashemitari, Ali Akbar Velayati
DOI: 10.5603/ARM.2019.0040
·
Pubmed: 31476012
·
Adv Respir Med 2019;87(4):239-242.

open access

Vol 87, No 4 (2019)
REVIEWS
Published online: 2019-08-30
Submitted: 2019-02-14
Accepted: 2019-07-16

Abstract

Introduction: Immunodeficient children are at a high risk of disseminated Bacillus Calmette-Guérin [BCG] infection. We assessed the literature on clinical manifestations of BCGosis in children with specific primary immunodeficiencies.

Material and methods: We conducted a systematic review of clinical practice articles by searching Medline, PubMed, Embase, Scopus, Web of Science and Google Scholar from their inception to date.

Results: Thirty-seven articles were included regarding BCG vaccination and its dissemination in children with primary immunodeficiencies. Articles on dissemination after intravesicular BCG were excluded from the study.

Conclusions: Since disseminated BCG vaccination may be the first manifestation of a primary immunodeficiency disease, a comprehensive search for immunological defects in children developing these problems after BCG vaccination seems rational.

Abstract

Introduction: Immunodeficient children are at a high risk of disseminated Bacillus Calmette-Guérin [BCG] infection. We assessed the literature on clinical manifestations of BCGosis in children with specific primary immunodeficiencies.

Material and methods: We conducted a systematic review of clinical practice articles by searching Medline, PubMed, Embase, Scopus, Web of Science and Google Scholar from their inception to date.

Results: Thirty-seven articles were included regarding BCG vaccination and its dissemination in children with primary immunodeficiencies. Articles on dissemination after intravesicular BCG were excluded from the study.

Conclusions: Since disseminated BCG vaccination may be the first manifestation of a primary immunodeficiency disease, a comprehensive search for immunological defects in children developing these problems after BCG vaccination seems rational.

Get Citation

Keywords

BCG, immunization, disseminated BCG infection, BCGosis, BCGitis

About this article
Title

Disseminated Bacille Calmette-Guérin infection at a glance: a mini review of the literature

Journal

Advances in Respiratory Medicine

Issue

Vol 87, No 4 (2019)

Article type

Review paper

Pages

239-242

Published online

2019-08-30

DOI

10.5603/ARM.2019.0040

Pubmed

31476012

Bibliographic record

Adv Respir Med 2019;87(4):239-242.

Keywords

BCG
immunization
disseminated BCG infection
BCGosis
BCGitis

Authors

Maryam Hassanzad
Ali Valinejadi
Sepideh Darougar
Seyed Karen Hashemitari
Ali Akbar Velayati

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