open access

Vol 73, No 1-2 (2005)
ORIGINAL PAPERS
Published online: 2008-02-18
Submitted: 2013-02-22
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The influence of mononucleosis infection on atopic disease development in children

Anna Stańczyk-Przyłuska, Anna Szmidt, Piotr Kuna, Izabela Kupryś-Lipińska, Anna Wolska
Pneumonol Alergol Pol 2005;73(1-2):20-24.

open access

Vol 73, No 1-2 (2005)
ORIGINAL PAPERS
Published online: 2008-02-18
Submitted: 2013-02-22

Abstract

The aim of the study was to determine whether infectious mononucleosis may trigger atopic symptoms or modulate their clinical course. Data from literature point out to such a relationship and attribute it to the influence of EBV on lymphocytes B and IL-4,IL-5,IL-10 and vIL-10 secretion stimulation.The authors examined 30 children who had suffered from symptomatic infectious mononucleosis 2-4 years previously, evaluating symptoms of allergic diseases and performing skin prick tests with selected inhalant and food allergens. The symptoms of atopic disease were found in 57 % in the mononucleosis group, a significantlyhigherpercentage(p<0.0001)thanin general population of chidren in Łódź (16%).The frequency of positive skin prick tests with common allergens was also significantlyhigher(60% vs. 27%,respectively).
Pneumonol. Alergol. Pol. 2005, 73, 18-22.

Abstract

The aim of the study was to determine whether infectious mononucleosis may trigger atopic symptoms or modulate their clinical course. Data from literature point out to such a relationship and attribute it to the influence of EBV on lymphocytes B and IL-4,IL-5,IL-10 and vIL-10 secretion stimulation.The authors examined 30 children who had suffered from symptomatic infectious mononucleosis 2-4 years previously, evaluating symptoms of allergic diseases and performing skin prick tests with selected inhalant and food allergens. The symptoms of atopic disease were found in 57 % in the mononucleosis group, a significantlyhigherpercentage(p<0.0001)thanin general population of chidren in Łódź (16%).The frequency of positive skin prick tests with common allergens was also significantlyhigher(60% vs. 27%,respectively).
Pneumonol. Alergol. Pol. 2005, 73, 18-22.
Get Citation

Keywords

EBV infections; atopic diseases; children

About this article
Title

The influence of mononucleosis infection on atopic disease development in children

Journal

Advances in Respiratory Medicine

Issue

Vol 73, No 1-2 (2005)

Pages

20-24

Published online

2008-02-18

Bibliographic record

Pneumonol Alergol Pol 2005;73(1-2):20-24.

Keywords

EBV infections
atopic diseases
children

Authors

Anna Stańczyk-Przyłuska
Anna Szmidt
Piotr Kuna
Izabela Kupryś-Lipińska
Anna Wolska

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