Vol 75, No 3 (2007)
REVIEWS
Published online: 2007-07-30
Submitted: 2013-02-22
Postoperative radiotherapy for non-small cell lung cancer: evidence based data and clinical practice
Lucyna Kępka, Krzysztof Bujko
Pneumonol Alergol Pol 2007;75(3):256-260.
Vol 75, No 3 (2007)
REVIEWS
Published online: 2007-07-30
Submitted: 2013-02-22
Abstract
According to the results of the metaanalyses the postoperative radiotherapy (PORT) after completely resected non-small cell
lung cancer (NSCLC) is detrimental for early stages (I and II). Its role for pN2 patients is unclear. Therefore, the PORT is not
recommended for patients after complete resection. However, the PORT metaanalysis raised many criticisms, because of
the methodological issues and inclusion of series with outdated radiotherapy techniques. The potential advantages and
disadvantages of PORT especially for stage III disease in the context of modern radiotherapy techniques and adjuvant
chemotherapy regimens are discussed. Such a prospective study exploring mainly the issues of cardiac and pulmonary
toxicity is currently conducted in Poland. The reasons of the common use of PORT, also for early stages of the disease, as
shown by patterns of care surveys are presented in the light of the quality of surgery issues.
Abstract
According to the results of the metaanalyses the postoperative radiotherapy (PORT) after completely resected non-small cell
lung cancer (NSCLC) is detrimental for early stages (I and II). Its role for pN2 patients is unclear. Therefore, the PORT is not
recommended for patients after complete resection. However, the PORT metaanalysis raised many criticisms, because of
the methodological issues and inclusion of series with outdated radiotherapy techniques. The potential advantages and
disadvantages of PORT especially for stage III disease in the context of modern radiotherapy techniques and adjuvant
chemotherapy regimens are discussed. Such a prospective study exploring mainly the issues of cardiac and pulmonary
toxicity is currently conducted in Poland. The reasons of the common use of PORT, also for early stages of the disease, as
shown by patterns of care surveys are presented in the light of the quality of surgery issues.
Keywords
non-small cell lung cancer; postoperative radiotherapy; adjuvant chemotherapy
Title
Postoperative radiotherapy for non-small cell lung cancer: evidence based data and clinical practice
Journal
Advances in Respiratory Medicine
Issue
Vol 75, No 3 (2007)
Pages
256-260
Published online
2007-07-30
Bibliographic record
Pneumonol Alergol Pol 2007;75(3):256-260.
Keywords
non-small cell lung cancer
postoperative radiotherapy
adjuvant chemotherapy
Authors
Lucyna Kępka
Krzysztof Bujko
About this article