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open access

Vol 75, No 4 (2007)
CASE REPORTS
Published online: 2007-10-26
Submitted: 2013-02-22
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Pulmonary malakoplakia and Rhodococcus equi infection. A report of two cases and review

Małgorzata Szołkowska, Renata Langfort, Ewa M. Szczepulska, Iwona Bestry, Jarosław Religioni
Pneumonol Alergol Pol 2007;75(4):398-407.

open access

Vol 75, No 4 (2007)
CASE REPORTS
Published online: 2007-10-26
Submitted: 2013-02-22

Abstract

Malakoplakia is a rare, chronic, granulomatous disease seen in immunocompromised patients, caused by multiple infectious agents, most often bacteria. Microscopically, accumulations of macrophages with granular cytoplasm and intra- or extracellular structures, called Michaelis-Gutmann bodies are characteristic. Main cause of pulmonary malakoplakia is Rhodococcus equi infection. We report two cases of pulmonary malakoplakia, in one case R. equi infection was confirmed. We also present a summary of recent knowledge about the pathogenesis, morphology and clinical course of the disease.

Abstract

Malakoplakia is a rare, chronic, granulomatous disease seen in immunocompromised patients, caused by multiple infectious agents, most often bacteria. Microscopically, accumulations of macrophages with granular cytoplasm and intra- or extracellular structures, called Michaelis-Gutmann bodies are characteristic. Main cause of pulmonary malakoplakia is Rhodococcus equi infection. We report two cases of pulmonary malakoplakia, in one case R. equi infection was confirmed. We also present a summary of recent knowledge about the pathogenesis, morphology and clinical course of the disease.

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Keywords

malakoplakia; Michaelis-Gutmann bodies; Rhodococcus equi

About this article
Title

Pulmonary malakoplakia and Rhodococcus equi infection. A report of two cases and review

Journal

Advances in Respiratory Medicine

Issue

Vol 75, No 4 (2007)

Pages

398-407

Published online

2007-10-26

Bibliographic record

Pneumonol Alergol Pol 2007;75(4):398-407.

Keywords

malakoplakia
Michaelis-Gutmann bodies
Rhodococcus equi

Authors

Małgorzata Szołkowska
Renata Langfort
Ewa M. Szczepulska
Iwona Bestry
Jarosław Religioni

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