open access

Vol 75, No 4 (2007)
ORIGINAL PAPERS
Published online: 2007-10-26
Submitted: 2013-02-22

Chemotherapy of advanced non small cell lung cancer: effect on survival and symptoms affecting quality of life

Janusz Rolski, Tomasz Zemełka, Marek Jasiówka, Grzegorz Czyżewicz, Ewelina Kojs-Pasińska
Pneumonol Alergol Pol 2007;75(4):343-348.

open access

Vol 75, No 4 (2007)
ORIGINAL PAPERS
Published online: 2007-10-26
Submitted: 2013-02-22

Abstract

Introduction: The study presents treatment results of 168 patients with non small cell lung cancer in stage IIIB and IV treated since year 2002 to 2006 in Oncological Center in Cracow.
Material and methods: Four regimens of chemotherapy: EP (cisplatin, vepesid), MVP (mitomycin C, vinblastin, cisplatin), PN (cisplatin,vinorelbin) and PG (cisplatin, gemcytabin) were used.
Results: Average survival time in group treated with MVP regimen was 7,8 months (median 4,3 months), PG 7,1 months (median 7,3 months), EP 10,2 months (median 7,5 months), PN 14,1 months (median 9,8 months). Differences in median survival time were not significant. Average time to progression in group treated with MVP regimen was 3,5 months (median 2,6 months), PG 5,2 months (median 5,8 months): EP 6,6 months (median 5,2 months), PN 6,7 months (median 5,6 months). Improvement in control of symptoms regarding dyspnea, pain and cough was reached in 60%, 38,7% and 60% of patients respectively. There were no significant differences between chemotherapy regimens regarding improvement in symptoms control.
Conclusions: Cisplatin + vinorelbin regimen can be recommended as standard method because of the best treatment results.

Keywords

non small cell lung cancer; chemotherapy; quality of life

About this article
Title

Chemotherapy of advanced non small cell lung cancer: effect on survival and symptoms affecting quality of life

Journal

Advances in Respiratory Medicine

Issue

Vol 75, No 4 (2007)

Pages

343-348

Published online

2007-10-26

Bibliographic record

Pneumonol Alergol Pol 2007;75(4):343-348.

Keywords

non small cell lung cancer
chemotherapy
quality of life

Authors

Janusz Rolski
Tomasz Zemełka
Marek Jasiówka
Grzegorz Czyżewicz
Ewelina Kojs-Pasińska

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