open access

Vol 76, No 5 (2008)
CASE REPORTS
Published online: 2008-09-17
Submitted: 2013-02-22
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Invasive aspergillosis of the paranasal sinuses, lung and brain

Krzysztof Kędziora, Jan Marek Słomiński, Katarzyna Gil, Maria Porzezińska, Agnieszka Gorzewska
Pneumonol Alergol Pol 2008;76(5):400-406.

open access

Vol 76, No 5 (2008)
CASE REPORTS
Published online: 2008-09-17
Submitted: 2013-02-22

Abstract

A case of invasive aspergillosis (IA) of paranasal sinuses, lung and brain with a fulminant fatal outcome is reported. A 43-year-old man with a history of skin carcinoma of the nasal region and a course of systemic corticosteroids, presented with symptoms of lung infection. Aspergillus fumigatus was cultured from respiratory and nasal samples. Erosion of adjacent bones of the nasal cavity was acknowledged, but no sinus surgery was performed. A computed tomography of the thorax showed thick-walled cavities of different sizes with air and scarce fluid levels in both lungs. Treatment with voriconazole was administered. The patient deteriorated in the ensuing 2 weeks because central nervous system involvement was observed. No aggressive surgical resection was performed and the patient died 2 weeks later. IA was not confirmed by histopathology because no necropsy was performed.

Abstract

A case of invasive aspergillosis (IA) of paranasal sinuses, lung and brain with a fulminant fatal outcome is reported. A 43-year-old man with a history of skin carcinoma of the nasal region and a course of systemic corticosteroids, presented with symptoms of lung infection. Aspergillus fumigatus was cultured from respiratory and nasal samples. Erosion of adjacent bones of the nasal cavity was acknowledged, but no sinus surgery was performed. A computed tomography of the thorax showed thick-walled cavities of different sizes with air and scarce fluid levels in both lungs. Treatment with voriconazole was administered. The patient deteriorated in the ensuing 2 weeks because central nervous system involvement was observed. No aggressive surgical resection was performed and the patient died 2 weeks later. IA was not confirmed by histopathology because no necropsy was performed.
Get Citation

Keywords

aspergillosis; fungal infection; lung infection; antifungal agents

About this article
Title

Invasive aspergillosis of the paranasal sinuses, lung and brain

Journal

Advances in Respiratory Medicine

Issue

Vol 76, No 5 (2008)

Pages

400-406

Published online

2008-09-17

Bibliographic record

Pneumonol Alergol Pol 2008;76(5):400-406.

Keywords

aspergillosis
fungal infection
lung infection
antifungal agents

Authors

Krzysztof Kędziora
Jan Marek Słomiński
Katarzyna Gil
Maria Porzezińska
Agnieszka Gorzewska

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