open access

Vol 79, No 2 (2011)
Published online: 2011-02-24
Submitted: 2013-02-22
Get Citation

The natural history of chronic obstructive pulmonary disease

David M. Mannino
Pneumonol Alergol Pol 2011;79(2):139-143.

open access

Vol 79, No 2 (2011)
Published online: 2011-02-24
Submitted: 2013-02-22

Abstract

This paper explores the natural history of chronic obstructive pulmonary disease (COPD), including our present understanding of COPD risk factors, phenotypes, and burden, along with COPD progression, including the traditional ‘accelerated lung function decline’ paradigm, to newer paradigms that include other factors. Questions remain unanswered, and there is considerable room for improvement. One of those questions is how the disease should best be defined. While this question has generated lively debate in the literature, it may not be the most important area with regard to advancing our understanding of the disease. The different phenotypes of COPD, particularly with regard to differential interventions and outcomes, is an area that should receive much more attention. Finally, a more holistic view of what comprises COPD progression, looking well beyond the traditional lung function decline paradigm, may also provide additional insights in how to better care for our patients.
Pneumonol. Alergol. Pol. 2011; 79, 2: 139-143

Abstract

This paper explores the natural history of chronic obstructive pulmonary disease (COPD), including our present understanding of COPD risk factors, phenotypes, and burden, along with COPD progression, including the traditional ‘accelerated lung function decline’ paradigm, to newer paradigms that include other factors. Questions remain unanswered, and there is considerable room for improvement. One of those questions is how the disease should best be defined. While this question has generated lively debate in the literature, it may not be the most important area with regard to advancing our understanding of the disease. The different phenotypes of COPD, particularly with regard to differential interventions and outcomes, is an area that should receive much more attention. Finally, a more holistic view of what comprises COPD progression, looking well beyond the traditional lung function decline paradigm, may also provide additional insights in how to better care for our patients.
Pneumonol. Alergol. Pol. 2011; 79, 2: 139-143
Get Citation
About this article
Title

The natural history of chronic obstructive pulmonary disease

Journal

Advances in Respiratory Medicine

Issue

Vol 79, No 2 (2011)

Pages

139-143

Published online

2011-02-24

Bibliographic record

Pneumonol Alergol Pol 2011;79(2):139-143.

Authors

David M. Mannino

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