Vol 79, No 3 (2011)
Review paper
Published online: 2011-04-21
Submitted: 2013-02-22
The role of non-invasive ventilation in the treatment of chronic obstructive pulmonary disease
Jacek Nasiłowski
Pneumonol Alergol Pol 2011;79(3):246-252.
Vol 79, No 3 (2011)
EDUKACJA. Zmniejszmy ciężar przewlekłej obturacyjnej choroby płuc (cz. II)
Published online: 2011-04-21
Submitted: 2013-02-22
Abstract
Non-invasive ventilation (NIV) is one of the most important developments in pulmonology over the past 15 years. Physiologic
effect of NIV is the same as that of invasive ventilation and consists of unloading respiratory muscles and improving
oxygenation. Nevertheless avoidance of ominous complications of intubation gives important advantages of NIV over
invasive ventilation. The principal indication for NIV is severe exacerbation of COPD, with uncompensated respiratory
acidosis. The efficacy of NIV in such population was proved, in controlled trials, to reduce: in-hospital mortality, the need for
intubation, the rate of complications and the length of stay in ICU and hospital. The role of NIV in the treatment of COPD
patients in stable state is less evident. However, there are several theoretical reasons and clinical evidences to use NIV in
home setting in patients with severe hypercapnia and symptoms of hypoventilation, in individuals who failed long-term
oxygen therapy (LTOT) treatment and in subjects with recurrent exacerbations. Moreover, NIV in acute and chronic setting
was recognized as cost-effective treatment.
Pneumonol. Alergol. Pol. 2011; 79, 3: 246-252
Abstract
Non-invasive ventilation (NIV) is one of the most important developments in pulmonology over the past 15 years. Physiologic
effect of NIV is the same as that of invasive ventilation and consists of unloading respiratory muscles and improving
oxygenation. Nevertheless avoidance of ominous complications of intubation gives important advantages of NIV over
invasive ventilation. The principal indication for NIV is severe exacerbation of COPD, with uncompensated respiratory
acidosis. The efficacy of NIV in such population was proved, in controlled trials, to reduce: in-hospital mortality, the need for
intubation, the rate of complications and the length of stay in ICU and hospital. The role of NIV in the treatment of COPD
patients in stable state is less evident. However, there are several theoretical reasons and clinical evidences to use NIV in
home setting in patients with severe hypercapnia and symptoms of hypoventilation, in individuals who failed long-term
oxygen therapy (LTOT) treatment and in subjects with recurrent exacerbations. Moreover, NIV in acute and chronic setting
was recognized as cost-effective treatment.
Pneumonol. Alergol. Pol. 2011; 79, 3: 246-252
Keywords
non-invasive ventilation; respiratory failure; COPD
Title
The role of non-invasive ventilation in the treatment of chronic obstructive pulmonary disease
Journal
Advances in Respiratory Medicine
Issue
Vol 79, No 3 (2011)
Article type
Review paper
Pages
246-252
Published online
2011-04-21
Bibliographic record
Pneumonol Alergol Pol 2011;79(3):246-252.
Keywords
non-invasive ventilation
respiratory failure
COPD