Tom 14, Nr 4 (2023)
Inne materiały uzgodnione z Redakcją
Opublikowany online: 2024-01-04
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Rola nutraceutyków w leczeniu dyslipidemii
Forum Zaburzeń Metabolicznych 2023;14(4):160-169.
Streszczenie
Rosnąca liczba pacjentów z dyslipidemią i związanych z nią powikłań sercowo-naczyniowych jest istotnym problemem klinicznym. Poszukuje się nowych rozwiązań terapeutycznych, które pomogą w optymalizacji profilu lipidowego pacjentów. Coraz większą uwagę przywiązuje się do stosowania bioaktywnych substancji — nutraceutyków. Liczne badania kliniczne potwierdzają skuteczność działania hipolipemizującego wybranych nutraceutyków w kontekście wspomagania farmakoterapii. Ze względu na profil działania wyróżnia się: 1) inhibitory jelitowego wchłaniania cholesterolu, 2) inhibitory wątrobowej syntezy cholesterolu, 3) składniki promujące wydalanie LDL-cholesterolu oraz 4) preparaty o mieszanym mechanizmie działania. Biorąc pod uwagę siłę dowodu naukowego, w pracy omówiono rolę i znaczenie wybranych nutraceutyków: czerwonego ryżu drożdżowego, steroli roślinnych, glukomannanu, czosnku, pantetyny, berberyny, zielonej herbaty, kwasów tłuszczowych z rodziny n-3 oraz kurkuminy.
Słowa kluczowe: sterole roślinneberberynamonakolina Kkwasy tłuszczowe n-3
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