Tom 7, Nr 4 (2016)
WYBRANE PROBLEMY KLINICZNE
Opublikowany online: 2017-01-30
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Neopteryna — nowe możliwości monitorowania miażdżycy
Forum Zaburzeń Metabolicznych 2016;7(4):176-181.
Streszczenie
Ostatnie lata przyniosły zmianę podejścia do patogenezy miażdżycy. Sugeruje się, że choroba ta jest przewlekłym procesem zapalnym. Zainteresowanie budzą nowe substancje służące do prognozowania i monitorowania miażdżycy. Jedną z nich jest neopteryna — wskaźnik aktywacji makrofagów i modulator stresu oksydacyjnego.
Słowa kluczowe: atherosclerosisendotheliumoxidative stressneopterin
Referencje
- Leonard SL. Pathophysiology of heart disease: A Collaborative Project of Medical Students and Faculty, 4 th ed. 2007: 129–152.
- Ross R, Ross R. Atherosclerosis--an inflammatory disease. N Engl J Med. 1999; 340(2): 115–126.
- Ross R, Glomset JA. The pathogenesis of atherosclerosis. NEJM . 1976; 295: 369–377.
- Davies PF, Reidy MA, Goode TB, et al. Scanning electron microscopy in the evaluation of endothelial integrity of the fatty lesion in atherosclerosis. Atherosclerosis. 1976; 25(1): 125–130.
- Cappecchi MR. Generating micewith targetet mutation. . Nature Med. 2001; 7: 1086–1090.
- Cines DB, Pollak ES, Buck CA, et al. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood. 1998; 91(10): 3527–3561.
- Fishman AP. Endothelium: a distributed organ of diverse capabilities. Ann N Y Acad Sci. 1982; 401: 1–8.
- Hamasaki S, Higano ST, Suwaidi JA, et al. Cholesterol-Lowering Treatment Is Associated With Improvement in Coronary Vascular Remodeling and Endothelial Function in Patients With Normal or Mildly Diseased Coronary Arteries. Arteriosclerosis, Thrombosis, and Vascular Biology. 2000; 20(3): 737–743.
- Boveris A. Biochemistry of free radicals: from electrons to tissues. Medicina (B Aires). 1998; 58(4): 350–356.
- Lusis A. Atherosclerosis. Nature. 2000; 407(6801): 233–241.
- Vergnani L, Hatrik S, Ricci F, et al. Effect of native and oxidized low-density lipoprotein on endothelial nitric oxide and superoxide production : key role of L-arginine availability. Circulation. 2000; 101(11): 1261–1266.
- Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005; 352(16): 1685–1695.
- Suzuki H, Kurihara Y, Takeya M, et al. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature. 1997; 386(6622): 292–296.
- Daugherty A, Rateri DL. T lymphocytes in atherosclerosis: the yin-yang of Th1 and Th2 influence on lesion formation. Circ Res. 2002; 90(10): 1039–1040.
- Laurat E, Poirier B, Tupin E, et al. In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice. Circulation. 2001; 104(2): 197–202.
- Pinderski LJ, Fischbein MP, Subbanagounder G, et al. Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient Mice by altering lymphocyte and macrophage phenotypes. Circ Res. 2002; 90(10): 1064–1071.
- Welt FGP, Rogers SD, Zhang X, et al. GP IIb/IIIa inhibition with eptifibatide lowers levels of soluble CD40L and RANTES after percutaneous coronary intervention. Catheter Cardiovasc Interv. 2004; 61(2): 185–189.
- Thom DH, Wang SP, Grayston JT, et al. Chlamydia pneumoniae strain TWAR antibody and angiographically demonstrated coronary artery disease. Arterioscler Thromb. 1991; 11(3): 547–551.
- Bayer M, Schmitz S, Westermann J, et al. Evaluation of a new enzyme-linked immunosorbent assay for the determination of neopterin. Clin Lab. 2005; 51(9-10): 495–504.
- Garcia-Moll X, Cole D, Zouridakis E, et al. Increased serum neopterin: a marker of coronary artery disease activity in women. Heart. 2000; 83(3): 346–350.
