open access

Vol 67, No 3 (2016)
Review paper
Submitted: 2015-08-10
Accepted: 2016-02-11
Published online: 2016-06-30
Get Citation

Insulin therapy — new directions of research

Edyta Cichocka, Anna Wietchy, Katarzyna Nabrdalik, Janusz Gumprecht
·
Pubmed: 27364374
·
Endokrynol Pol 2016;67(3):314-324.

open access

Vol 67, No 3 (2016)
Review Article
Submitted: 2015-08-10
Accepted: 2016-02-11
Published online: 2016-06-30

Abstract

Insulin therapy is the most effective method of lowering blood glucose. Over 100 years have passed the studies for the optimisation of insulin action. To date, subcutaneous insulin administration has been the basic route of insulin delivery. The search for insulin therapy is simultaneously conducted in the following directions: the optimisation of insulin action, automatisation, and the decrease in the invasiveness of insulin delivery methods.

The optimisation of insulin action has led to the discovery of ultra-rapid-acting human insulin analogues, ultra-long-acting human insulin analogues, and biosimilar insulin. Automatisation referred to the “artificial pancreas” and closing the loop system in insulin pump therapy. The decrease in the invasiveness of insulin delivery methods is focused on alternative routes of insulin administration. (Endokrynol Pol 2016; 67 (3): 314–324)

Abstract

Insulin therapy is the most effective method of lowering blood glucose. Over 100 years have passed the studies for the optimisation of insulin action. To date, subcutaneous insulin administration has been the basic route of insulin delivery. The search for insulin therapy is simultaneously conducted in the following directions: the optimisation of insulin action, automatisation, and the decrease in the invasiveness of insulin delivery methods.

The optimisation of insulin action has led to the discovery of ultra-rapid-acting human insulin analogues, ultra-long-acting human insulin analogues, and biosimilar insulin. Automatisation referred to the “artificial pancreas” and closing the loop system in insulin pump therapy. The decrease in the invasiveness of insulin delivery methods is focused on alternative routes of insulin administration. (Endokrynol Pol 2016; 67 (3): 314–324)

Get Citation

Keywords

diabetes; new insulin; artificial pancreans; insulin pump; alternative route of insulin therapy

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About this article
Title

Insulin therapy — new directions of research

Journal

Endokrynologia Polska

Issue

Vol 67, No 3 (2016)

Article type

Review paper

Pages

314-324

Published online

2016-06-30

Page views

6409

Article views/downloads

6476

DOI

10.5603/EP.2016.0044

Pubmed

27364374

Bibliographic record

Endokrynol Pol 2016;67(3):314-324.

Keywords

diabetes
new insulin
artificial pancreans
insulin pump
alternative route of insulin therapy

Authors

Edyta Cichocka
Anna Wietchy
Katarzyna Nabrdalik
Janusz Gumprecht

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