open access
Insulin therapy — new directions of research
open access
Abstract
Insulin therapy is the most effective method of lowering blood glucose. Over 100 years have passed the studies for the optimisation of insulin action. To date, subcutaneous insulin administration has been the basic route of insulin delivery. The search for insulin therapy is simultaneously conducted in the following directions: the optimisation of insulin action, automatisation, and the decrease in the invasiveness of insulin delivery methods.
The optimisation of insulin action has led to the discovery of ultra-rapid-acting human insulin analogues, ultra-long-acting human insulin analogues, and biosimilar insulin. Automatisation referred to the “artificial pancreas” and closing the loop system in insulin pump therapy. The decrease in the invasiveness of insulin delivery methods is focused on alternative routes of insulin administration. (Endokrynol Pol 2016; 67 (3): 314–324)
Abstract
Insulin therapy is the most effective method of lowering blood glucose. Over 100 years have passed the studies for the optimisation of insulin action. To date, subcutaneous insulin administration has been the basic route of insulin delivery. The search for insulin therapy is simultaneously conducted in the following directions: the optimisation of insulin action, automatisation, and the decrease in the invasiveness of insulin delivery methods.
The optimisation of insulin action has led to the discovery of ultra-rapid-acting human insulin analogues, ultra-long-acting human insulin analogues, and biosimilar insulin. Automatisation referred to the “artificial pancreas” and closing the loop system in insulin pump therapy. The decrease in the invasiveness of insulin delivery methods is focused on alternative routes of insulin administration. (Endokrynol Pol 2016; 67 (3): 314–324)
Keywords
diabetes; new insulin; artificial pancreans; insulin pump; alternative route of insulin therapy
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About this articleTitle
Insulin therapy — new directions of research
Journal
Issue
Article type
Review paper
Pages
314-324
Published online
2016-06-30
Page views
6191
Article views/downloads
6262
DOI
Pubmed
Bibliographic record
Endokrynol Pol 2016;67(3):314-324.
Keywords
diabetes
new insulin
artificial pancreans
insulin pump
alternative route of insulin therapy
Authors
Edyta Cichocka
Anna Wietchy
Katarzyna Nabrdalik
Janusz Gumprecht
