open access
Audit on bedside chemical pleurodesis in palliative care setting: Brunei experience


- RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam
open access
Abstract
Background: Malignant pleural effusion typically is a sign of aggressive and advance disease with generally short life expectancy. This cause a lot of burden symptomatically to patients with advance malignancy. Hence, a lot of patients are made known early to palliative service to help optimizing patients’ symptomology. One of the procedures to help preventing recurrence of symptomatic malignant pleural effusion is bedside chemical pleurodesis following thoracocentesis. The aim of this audit is to assess our efficacy and safety of doing the above procedure in a palliative setting.
Patients and methods: Retrospective electronic records of patients were reviewed from January 2020 until March 2022. Malignant pleural effusion were confirm by cytological assessment of pleural fluid following chest tube drainage. Chemical pleurodesis was done by pleural fluid instillation of bleomycin, performed bedside by palliative physicians.
Results: Twenty patients were identified with 7 cases were male and 13 cases were female. Mean age was 69.2 with 55% of them suffered from lung malignancy. Complete response is seen in 45% and partial response is seen in 20%. Failure rate is at 35%. The complications were minimal with only 5% of patient had fever and 10% had pleuritic pain.
Conclusions: The audit shows bedside chemical pleurodesis perform by palliative physicians is as efficacious and safe comparing to when it is done by other specialties. It helps improve symptoms to 65% of our patient and thus improve quality of life.
Abstract
Background: Malignant pleural effusion typically is a sign of aggressive and advance disease with generally short life expectancy. This cause a lot of burden symptomatically to patients with advance malignancy. Hence, a lot of patients are made known early to palliative service to help optimizing patients’ symptomology. One of the procedures to help preventing recurrence of symptomatic malignant pleural effusion is bedside chemical pleurodesis following thoracocentesis. The aim of this audit is to assess our efficacy and safety of doing the above procedure in a palliative setting.
Patients and methods: Retrospective electronic records of patients were reviewed from January 2020 until March 2022. Malignant pleural effusion were confirm by cytological assessment of pleural fluid following chest tube drainage. Chemical pleurodesis was done by pleural fluid instillation of bleomycin, performed bedside by palliative physicians.
Results: Twenty patients were identified with 7 cases were male and 13 cases were female. Mean age was 69.2 with 55% of them suffered from lung malignancy. Complete response is seen in 45% and partial response is seen in 20%. Failure rate is at 35%. The complications were minimal with only 5% of patient had fever and 10% had pleuritic pain.
Conclusions: The audit shows bedside chemical pleurodesis perform by palliative physicians is as efficacious and safe comparing to when it is done by other specialties. It helps improve symptoms to 65% of our patient and thus improve quality of life.
Keywords
malignant pleural effusion, pleurodesis, palliative care


Title
Audit on bedside chemical pleurodesis in palliative care setting: Brunei experience
Journal
Palliative Medicine in Practice
Issue
Article type
Research paper
Published online
2023-01-16
Page views
38
Article views/downloads
16
DOI
10.5603/PMPI.a2023.0004
Keywords
malignant pleural effusion
pleurodesis
palliative care
Authors
Muhammad Yusuf Shaharudin


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