open access

Vol 14, No 3 (2020)
Review paper
Published online: 2020-08-17
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Ketamine — a unique adjuvant drug in pain treatment

Anna Rupniewska-Ładyko1
·
Palliat Med Pract 2020;14(3):192-197.
Affiliations
  1. Centre of Postgraduate Medical Education, Warsaw, Poland

open access

Vol 14, No 3 (2020)
Review paper
Published online: 2020-08-17

Abstract

Ketamine is an anaesthetic with unique properties. Synthesised for the first time in the early 1960s, it causes
dissociative anaesthesia, sedation, amnesia, and analgesia. Due to hallucinogenic effects, the use of the
drug was significantly reduced in the 1980s. At present, ketamine is used to treat acute and chronic pain,
especially pain resistant to other pain management methods. Ketamine can be effective in the treatment
of chronic neuropathic pain syndromes, prevention of secondary hyperalgesia in burn injuries, treatment
of muscle pain in patients with fibromyalgia, metastatic bone pain and treatment of pain caused by oral
mucositis.

Abstract

Ketamine is an anaesthetic with unique properties. Synthesised for the first time in the early 1960s, it causes
dissociative anaesthesia, sedation, amnesia, and analgesia. Due to hallucinogenic effects, the use of the
drug was significantly reduced in the 1980s. At present, ketamine is used to treat acute and chronic pain,
especially pain resistant to other pain management methods. Ketamine can be effective in the treatment
of chronic neuropathic pain syndromes, prevention of secondary hyperalgesia in burn injuries, treatment
of muscle pain in patients with fibromyalgia, metastatic bone pain and treatment of pain caused by oral
mucositis.

Get Citation

Keywords

ketamine, pain, adjuvant, analgesia

About this article
Title

Ketamine — a unique adjuvant drug in pain treatment

Journal

Palliative Medicine in Practice

Issue

Vol 14, No 3 (2020)

Article type

Review paper

Pages

192-197

Published online

2020-08-17

Page views

884

Article views/downloads

640

DOI

10.5603/PMPI.2020.0023

Bibliographic record

Palliat Med Pract 2020;14(3):192-197.

Keywords

ketamine
pain
adjuvant
analgesia

Authors

Anna Rupniewska-Ładyko

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