Vol 13, No 4 (2019)
Case report
Published online: 2020-01-03

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Paraneoplastic hypertrophic pulmonary osteoarthropathy and pain management: a case report

Aleksandra Masłowska1, Marcin Rutkowski1, Alba Gabriela Picco Brunetto2
Palliat Med Pract 2019;13(4):248-251.

Abstract

Hypertrophic osteoarthropathy (HOA) is a syndrome that consists of periostitis, digital clubbing, and painful
polyarthropathy. The management and prognosis of HOA is dependent on the underlying disease process.
Recognising and treating it accordingly will reduce the symptom burden of patients. We present a case
of a patient diagnosed with non-small cell lung cancer and HOA suffering from severe pain, and review
specific therapies for the management of HOA-related pain.

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References

  1. Kilaru M, Vitale C, Montagnini M. Pain management in hypertrophic pulmonary osteoarthropathy: an illustrative case and review. Am J Hosp Palliat Care. 2012; 29(4): 302–307.
  2. Ribigan AC, Bajenaru OL, Antochi FA, et al. Nociceptive pain unmasking a serious pathology - paraneoplastic hypertrophic osteoarthropathy: A case report. Medicine (Baltimore). 2019; 98(23): e15900.
  3. Nguyen S, Hojjati M. Review of current therapies for secondary hypertrophic pulmonary osteoarthropathy. Clin Rheumatol. 2011; 30(1): 7–13.
  4. Pourmorteza M, Baumrucker SJ, Al-Sheyyab A, et al. Hypertrophic Pulmonary Osteoarthropathy: A Rare But Treatable Condition in Palliative Medicine. J Pain Symptom Manage. 2015; 50(2): 263–267.
  5. Ito T, Goto K, Yoh K, et al. Hypertrophic pulmonary osteoarthropathy as a paraneoplastic manifestation of lung cancer. J Thorac Oncol. 2010; 5(7): 976–980.
  6. Chakraborty RK, Sharma S. Secondary Hypertrophic Osteoarthropathy. In: StatPearls. Treasure Island, FL, 2019. https://www.ncbi.nlm.nih.gov/ books/NBK513342/ (April 2019).
  7. Sonthalia N, Mukherjee K, Saha A, et al. Treatment of hypertrophic osteoarthropathy in the case of pulmonary metastasis secondary-to-nasopharyngeal carcinoma with zoledronic acid: an enlightening experience. BMJ Case Rep. 2012; 2012.
  8. Jayakar BA, Abelson AG, Yao Q. Treatment of hypertrophic osteoarthropathy with zoledronic acid: case report and review of the literature. Semin Arthritis Rheum. 2011; 41(2): 291–296.
  9. Tachibana I, Gehi D, Rubin CD. Treatment of Hypertrophic Osteoarthropathy With Underlying Pulmonary Adenocarcinoma Using Zoledronic Acid. J Clin Rheumatol. 2015; 21(6): 333–334.
  10. Angel-Moreno Maroto A, Martínez-Quintana E, Suárez-Castellano L, et al. Painful hypertrophic osteoarthropathy successfully treated with octreotide. The pathogenetic role of vascular endothelial growth factor (VEGF). Rheumatology (Oxford). 2005; 44(10): 1326–1327.
  11. Openshaw MR, Rowan CS, Grumett S. Atypical hypertrophic osteoartropathy as a presenting complaint in a non-smoker. J Med Cases. 2013; 4: 204–207.