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What do we know about influence of opioids on immune system?
open access
Abstract
Opioid effects on the immune system is a complex phenomenon which depends on the following variables: type of the opioid drug, the nature of the response (humoral or cellular), and the type of cells involved in its course. Macrophages appear to play an important role in modulating the signal of the opioid.
This is confirmed by the results of research conducted by a group of researchers from Krakow, which evaluated the effect of treatment with different opioids on the parameters of humoral and cellular immunity. While studies with morphine, fentanyl, and methadone has been completed, research on oxycodone and buprenorphine are still conducted. The work will be covered by the so far obtained results of experimental usage of these opioids.
Abstract
Opioid effects on the immune system is a complex phenomenon which depends on the following variables: type of the opioid drug, the nature of the response (humoral or cellular), and the type of cells involved in its course. Macrophages appear to play an important role in modulating the signal of the opioid.
This is confirmed by the results of research conducted by a group of researchers from Krakow, which evaluated the effect of treatment with different opioids on the parameters of humoral and cellular immunity. While studies with morphine, fentanyl, and methadone has been completed, research on oxycodone and buprenorphine are still conducted. The work will be covered by the so far obtained results of experimental usage of these opioids.
Keywords
opioids, immune system, humoral and cellular immunity
About this articleTitle
What do we know about influence of opioids on immune system?
Journal
Palliative Medicine in Practice
Issue
Article type
Review paper
Pages
59-65
Published online
2016-11-29
Page views
711
Article views/downloads
2346
Bibliographic record
Medycyna Paliatywna w Praktyce 2016;10(2):59-65.
Keywords
opioids
immune system
humoral and cellular immunity
Authors
Iwona Filipczak-Bryniarska
Krzysztof Bryniarski
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