open access

Vol 10, No 2 (2016)
Review paper
Published online: 2016-11-29
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What do we know about influence of opioids on immune system?

Iwona Filipczak-Bryniarska, Krzysztof Bryniarski
Medycyna Paliatywna w Praktyce 2016;10(2):59-65.

open access

Vol 10, No 2 (2016)
Review articles
Published online: 2016-11-29

Abstract

Opioid effects on the immune system is a complex phenomenon which depends on the following variables: type of the opioid drug, the nature of the response (humoral or cellular), and the type of cells involved in its course. Macrophages appear to play an important role in modulating the signal of the opioid.

This is confirmed by the results of research conducted by a group of researchers from Krakow, which evaluated the effect of treatment with different opioids on the parameters of humoral and cellular immunity. While studies with morphine, fentanyl, and methadone has been completed, research on oxycodone and buprenorphine are still conducted. The work will be covered by the so far obtained results of experimental usage of these opioids.

Abstract

Opioid effects on the immune system is a complex phenomenon which depends on the following variables: type of the opioid drug, the nature of the response (humoral or cellular), and the type of cells involved in its course. Macrophages appear to play an important role in modulating the signal of the opioid.

This is confirmed by the results of research conducted by a group of researchers from Krakow, which evaluated the effect of treatment with different opioids on the parameters of humoral and cellular immunity. While studies with morphine, fentanyl, and methadone has been completed, research on oxycodone and buprenorphine are still conducted. The work will be covered by the so far obtained results of experimental usage of these opioids.

Get Citation

Keywords

opioids, immune system, humoral and cellular immunity

About this article
Title

What do we know about influence of opioids on immune system?

Journal

Palliative Medicine in Practice

Issue

Vol 10, No 2 (2016)

Article type

Review paper

Pages

59-65

Published online

2016-11-29

Bibliographic record

Medycyna Paliatywna w Praktyce 2016;10(2):59-65.

Keywords

opioids
immune system
humoral and cellular immunity

Authors

Iwona Filipczak-Bryniarska
Krzysztof Bryniarski

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