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Clinical features, diagnosis and management of serpiginuos choroiditis
Affiliations- Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
- Deparment of Immunology, Transplant Medicine and Internal Diseases, Medical University of Warsaw, Warsaw, Poland
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Abstract
Classic serpiginous choroiditis (CSC) is a rare bilateral, multifocal, recurrent inflammatory disease of the choroid and retina observed mainly in young and middle-aged male patients. We present three cases of otherwise healthy men (ages 30, 52, and 54 years) with the diagnosis of CSC based on clinical and multimodal imaging findings.
During the observation period, slow progression of the fundus changes was noted in each patient despite various individualized immunosuppressive treatments (corticosteroids, cyclosporin, cyclophosphamide, azathioprine) used. Progressive macular involvement was associated with a significant irreversible bilateral reduction in visual acuity. The aim of the study is to present the clinical features of CSC, possible diagnostic and therapeutic options, and to familiarize the reader with specific clinical cases.
Abstract
Classic serpiginous choroiditis (CSC) is a rare bilateral, multifocal, recurrent inflammatory disease of the choroid and retina observed mainly in young and middle-aged male patients. We present three cases of otherwise healthy men (ages 30, 52, and 54 years) with the diagnosis of CSC based on clinical and multimodal imaging findings.
During the observation period, slow progression of the fundus changes was noted in each patient despite various individualized immunosuppressive treatments (corticosteroids, cyclosporin, cyclophosphamide, azathioprine) used. Progressive macular involvement was associated with a significant irreversible bilateral reduction in visual acuity. The aim of the study is to present the clinical features of CSC, possible diagnostic and therapeutic options, and to familiarize the reader with specific clinical cases.
Keywords
classic serpiginous choroiditis (CSC); fluorescein angiography; indocyanine green angiography; macular involvement; permanent damage of the retina; immunosuppressive treatment
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About this articleTitle
Clinical features, diagnosis and management of serpiginuos choroiditis
Journal
Issue
Vol 7 (2022): Continuous Publishing
Article type
Case report
Pages
127-135
Published online
2022-09-05
Page views
3695
Article views/downloads
624
DOI
Bibliographic record
Ophthalmol J 2022;7:127-135.
Keywords
classic serpiginous choroiditis (CSC)
fluorescein angiography
indocyanine green angiography
macular involvement
permanent damage of the retina
immunosuppressive treatment
Authors
Magdalena Kępka
Joanna Brydak-Godowska
Joanna Ciszewska
Monika Turczyńska
Michał Ciszek
Dariusz Kęcik
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