open access

Vol 46, No 1 (2012)
OPIS PRZYPADKU
Submitted: 2011-02-26
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Percutaneous closure of the left atrial appendage to prevent ischaemic stroke in patients with atrial fibrillation who require but have contraindications to oral anticoagulation

Przemysław Węglarz, Tomasz Bochenek, Maciej Świat, Ewa Konarska-Kuszewska, Wojciech Wróbel, Bogusława Czyrnik, Katarzyna Spisak-Borowska, Grzegorz Opala, Maria Trusz-Gluza
DOI: 10.5114/ninp.2012.27178
·
Neurol Neurochir Pol 2012;46(1):87-91.

open access

Vol 46, No 1 (2012)
OPIS PRZYPADKU
Submitted: 2011-02-26

Abstract

Atrial fibrillation (AF) is associated with a five-fold increased risk for stroke due to cardioembolic events. Most strokes in patients with AF arise from thrombus formation in the left atrial appendage (LAA). Oral anticoagulation is a standard treatment of AF patients with high risk of stroke. However, the main drawbacks of oral anticoagulation are high risk of major bleeding and imperfect effectiveness dependent on a very narrow therapeutic range. In this article, based on two case reports, we describe a method of percutaneous closure of the LAA. We discuss indications, describe the procedure and mention possible complications. LAA closure seems to be a promising tool to prevent AF-related strokes in a selected group of patients.

Abstract

Atrial fibrillation (AF) is associated with a five-fold increased risk for stroke due to cardioembolic events. Most strokes in patients with AF arise from thrombus formation in the left atrial appendage (LAA). Oral anticoagulation is a standard treatment of AF patients with high risk of stroke. However, the main drawbacks of oral anticoagulation are high risk of major bleeding and imperfect effectiveness dependent on a very narrow therapeutic range. In this article, based on two case reports, we describe a method of percutaneous closure of the LAA. We discuss indications, describe the procedure and mention possible complications. LAA closure seems to be a promising tool to prevent AF-related strokes in a selected group of patients.

Get Citation

Keywords

ischaemic stroke, left atrial appendage, antithrombotic therapy

About this article
Title

Percutaneous closure of the left atrial appendage to prevent ischaemic stroke in patients with atrial fibrillation who require but have contraindications to oral anticoagulation

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 46, No 1 (2012)

Pages

87-91

DOI

10.5114/ninp.2012.27178

Bibliographic record

Neurol Neurochir Pol 2012;46(1):87-91.

Keywords

ischaemic stroke
left atrial appendage
antithrombotic therapy

Authors

Przemysław Węglarz
Tomasz Bochenek
Maciej Świat
Ewa Konarska-Kuszewska
Wojciech Wróbel
Bogusława Czyrnik
Katarzyna Spisak-Borowska
Grzegorz Opala
Maria Trusz-Gluza

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