dostęp otwarty

Ahead of print
Sprawozdanie
Opublikowany online: 2018-09-14
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Novel synthesis of magnetic nanoparticles conjugation with Perfluorocarbon Nano-bubbles for potential adjunct therapy of acute myocardial ischemia

Mark C Arokiaraj
DOI: 10.5603/FC.a2018.0095

dostęp otwarty

Ahead of print
Sprawozdanie
Opublikowany online: 2018-09-14

Streszczenie

Background

The study was performed in search of a novel adjunct agent for myocardial salvage in acute myocardial ischemia.

Methods and results

This is a report of conjugation between perfluorocarbon

nanobubbles with multifunctional biocompatible magnetic nanoparticles. It was possible to synthesize the conjugation of multifunctional biocompatible magnetic nanoparticles with perfluorocarbon nanobubbles. The potential nano-size magnetic product could cross the deranged endothelial borders in the ischemic penumbra regions, and could help in myocardial salvage. Furthermore, the particles could be focused to the target region using magnetic micromesh technique.

Conclusion

A conjugation between magnetic nanoparticles and PFC nano-bubbles is possible. Further studies need to be performed to explore the potential uses.

Streszczenie

Background

The study was performed in search of a novel adjunct agent for myocardial salvage in acute myocardial ischemia.

Methods and results

This is a report of conjugation between perfluorocarbon

nanobubbles with multifunctional biocompatible magnetic nanoparticles. It was possible to synthesize the conjugation of multifunctional biocompatible magnetic nanoparticles with perfluorocarbon nanobubbles. The potential nano-size magnetic product could cross the deranged endothelial borders in the ischemic penumbra regions, and could help in myocardial salvage. Furthermore, the particles could be focused to the target region using magnetic micromesh technique.

Conclusion

A conjugation between magnetic nanoparticles and PFC nano-bubbles is possible. Further studies need to be performed to explore the potential uses.

Pobierz cytowanie

Słowa kluczowe

Myocardial acute infarction, Pharmacology, Basic Science Research, Hypoxia

Informacje o artykule
Tytuł

Novel synthesis of magnetic nanoparticles conjugation with Perfluorocarbon Nano-bubbles for potential adjunct therapy of acute myocardial ischemia

Czasopismo

Folia Cardiologica

Numer

Ahead of print

Data publikacji on-line

2018-09-14

DOI

10.5603/FC.a2018.0095

Słowa kluczowe

Myocardial acute infarction
Pharmacology
Basic Science Research
Hypoxia

Autorzy

Mark C Arokiaraj

Referencje (8)
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