open access

Vol 11, No 2 (2016)
Review Papers
Published online: 2016-05-12
Get Citation

Circulatory system in patients with systemic lupus erythematosus

Anna Chrzanowska, Katarzyna Irzyk, Iwona Dudzik-Niewiadomska, Piotr Bienias, Michał Ciurzyński
DOI: 10.5603/FC.2016.0017
·
Folia Cardiologica 2016;11(2):111-118.

open access

Vol 11, No 2 (2016)
Review Papers
Published online: 2016-05-12

Abstract

Systemic lupus erythematosus (SLE) is a systemic chronic, inflammatory, autoimmune disease, characterized by various clinical manifestations and production of multiple autoantibodies. Complex immune system dysfunctions as well as chronic inflammatory processes lead to internal organs and tissue failure.

The most common cardiovascular manifestations among patients with SLE include accelerated coronary heart disease, pericarditis, myocarditis, valvular disease, Libman–Sacks nonbacterial endocarditis - the most characteristic cardiac manifestation of the SLE, conduction abnormalities, pulmonary hypertension, thromboembolic events, hypertension and heart failure. Accelerated atherosclerosis with coronary heart disease is of key importance for prognosis, particularly among young women. An increased risk of cardiovascular events among patients with SLE has been confirmed in multiple studies. Getting closer to understanding multiple mechanisms of cardiovascular disease and pathogenesis of atherosclerosis in SLE is critical to lower mortality rate in this group population. The aim of this article is to present aetiology and cardiovascular manifestations processes of SLE.

Abstract

Systemic lupus erythematosus (SLE) is a systemic chronic, inflammatory, autoimmune disease, characterized by various clinical manifestations and production of multiple autoantibodies. Complex immune system dysfunctions as well as chronic inflammatory processes lead to internal organs and tissue failure.

The most common cardiovascular manifestations among patients with SLE include accelerated coronary heart disease, pericarditis, myocarditis, valvular disease, Libman–Sacks nonbacterial endocarditis - the most characteristic cardiac manifestation of the SLE, conduction abnormalities, pulmonary hypertension, thromboembolic events, hypertension and heart failure. Accelerated atherosclerosis with coronary heart disease is of key importance for prognosis, particularly among young women. An increased risk of cardiovascular events among patients with SLE has been confirmed in multiple studies. Getting closer to understanding multiple mechanisms of cardiovascular disease and pathogenesis of atherosclerosis in SLE is critical to lower mortality rate in this group population. The aim of this article is to present aetiology and cardiovascular manifestations processes of SLE.

Get Citation

Keywords

systemic lupus erythematosus; cardiovascular manifestations; atherosclerosis; coronary heart disease

About this article
Title

Circulatory system in patients with systemic lupus erythematosus

Journal

Folia Cardiologica

Issue

Vol 11, No 2 (2016)

Pages

111-118

Published online

2016-05-12

DOI

10.5603/FC.2016.0017

Bibliographic record

Folia Cardiologica 2016;11(2):111-118.

Keywords

systemic lupus erythematosus
cardiovascular manifestations
atherosclerosis
coronary heart disease

Authors

Anna Chrzanowska
Katarzyna Irzyk
Iwona Dudzik-Niewiadomska
Piotr Bienias
Michał Ciurzyński

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

 

Wydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl