Vol 14, No 4 (2019)
Conference report / Report
Published online: 2018-09-14
Novel synthesis of magnetic nanoparticles conjugation with perfluorocarbon nanobubbles for potential adjunct therapy of acute myocardial ischaemia
DOI: 10.5603/FC.a2018.0095
Folia Cardiologica 2019;14(4):425-427.
Abstract
Introduction. This study was performed in search of a novel adjunct agent for myocardial salvage in acute myocardial ischaemia.
Methods and results. This is a report of conjugation between perfluorocarbon nanobubbles with multifunctional biocompatible magnetic nanoparticles. It was possible to synthesise the conjugation of multifunctional biocompatible magnetic nanoparticles with perfluorocarbon nanobubbles. The potential nano-size magnetic product could cross the deranged endothelial borders in the ischaemic penumbra regions, and could help in myocardial salvage. Furthermore, the particles could be focused to the target region using the magnetic micromesh technique.
Conclusions. A conjugation between magnetic nanoparticles and PFC nano-bubbles is possible. Further studies need to be performed to explore the potential uses.
Keywords: acute myocardial infarctionpharmacologybasic science researchhypoxia
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