Exploring the Complexity: Understanding the Role and Clinical Implications of Pericardial Adipose Tissue in Cardiovascular Diseases Pathophysiology
Abstract
Epicardial adipose tissue (EAT) is an important area of research related to cardiovascular disease. It plays a key role in cardiac and coronary vascular function by storing fatty acids and regulating coronary microcirculation. In this review, we discuss the function of EAT and its relationship to cardiovascular disease. The relationship between EAT and diseases such as coronary artery disease and heart failure is analysed, with a focus on pathophysiological mechanisms. In the following section, we present methods for imaging EAT and possible therapeutic strategies: lifestyle changes, bariatric surgery, and pharmacotherapy. Understanding the role of EAT may contribute to the development of more effective therapeutic strategies for the treatment of cardiovascular disease. It is presumed that EAT volume reduction may be beneficial for the heart, and cardiometabolic drugs may be a potentially effective therapy, but they require further research to confirm their efficacy and safety.
Keywords: epicardial Adipose TissueCardiovascular diseasesHeart Failure
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