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Vol 2, No 1 (2006)
Prace poglądowe
Published online: 2006-02-07
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Acquired and congenital lipodystrophy

Joanna Oświęcimska, Katarzyna Ziora, Antoni Dyduch
Endokrynol. Otył. Zab. Przem. Mat 2006;2(1):22-29.

open access

Vol 2, No 1 (2006)
Prace poglądowe
Published online: 2006-02-07

Abstract

Lipodystrophies are heterogenic and rare diseases of various ethiology. Generalized or partial (limited to some parts of the body lipoatrophy) localization is the main feature of lipodystrophies. These diseases are frequently accompanied by metabolic disturbances as: insuline resistance, hyperinsulinism, glucose intolerance or type 2 diabetes and hypertriglycerydaemia. Metabolic distrurbances in lipodystrophies are similar but more intensive to the metabolic syndrome without obesity. Patients with lipodystrophy very often reveal acanthosis nigricans, liver steatosis and polycystic ovary syndrome. Lipodystrophies are divided into generalized and partial types. The ethiology of lipodystrophies is diverse and unclear - some of them have genetic genesis and in some immunological factors are underlined. The review of lipodystrophies’ latest opinions concerned ethiopatogenesis, symptoms and treatment are presented in this paper.

Abstract

Lipodystrophies are heterogenic and rare diseases of various ethiology. Generalized or partial (limited to some parts of the body lipoatrophy) localization is the main feature of lipodystrophies. These diseases are frequently accompanied by metabolic disturbances as: insuline resistance, hyperinsulinism, glucose intolerance or type 2 diabetes and hypertriglycerydaemia. Metabolic distrurbances in lipodystrophies are similar but more intensive to the metabolic syndrome without obesity. Patients with lipodystrophy very often reveal acanthosis nigricans, liver steatosis and polycystic ovary syndrome. Lipodystrophies are divided into generalized and partial types. The ethiology of lipodystrophies is diverse and unclear - some of them have genetic genesis and in some immunological factors are underlined. The review of lipodystrophies’ latest opinions concerned ethiopatogenesis, symptoms and treatment are presented in this paper.

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Keywords

acquired lipodystrophies; congenital lipodystrophies; partial lipodystrophies; generalized lipodystrophies; Berardinelli-Seip syndrome; Lawrence syndrome; Barraquer-Simons syndrome; Dunningan syndrome; HIV infection

About this article
Title

Acquired and congenital lipodystrophy

Journal

Endocrinology, Obesity and Metabolic Disorders

Issue

Vol 2, No 1 (2006)

Pages

22-29

Published online

2006-02-07

Page views

2218

Article views/downloads

13990

Bibliographic record

Endokrynol. Otył. Zab. Przem. Mat 2006;2(1):22-29.

Keywords

acquired lipodystrophies
congenital lipodystrophies
partial lipodystrophies
generalized lipodystrophies
Berardinelli-Seip syndrome
Lawrence syndrome
Barraquer-Simons syndrome
Dunningan syndrome
HIV infection

Authors

Joanna Oświęcimska
Katarzyna Ziora
Antoni Dyduch

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