open access

Vol 63, No 4 (2012)
Original papers
Published online: 2012-08-30
Submitted: 2013-02-15
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Comparison and assessment of thyroid morphology and function in inhabitants of Lower Silesia before and after administration of a single dose of iodine-containing contrast agent during cardiac intervention procedure

Katarzyna Skórkowska-Telichowska, Joanna Kosińska, Rafał Szymczak, Dominika Tuchendler, Renata Tuchendler, Artur Telichowski, Grzegorz Szajn, Marek Bolanowski
Endokrynologia Polska 2012;63(4):294-299.

open access

Vol 63, No 4 (2012)
Original papers
Published online: 2012-08-30
Submitted: 2013-02-15

Abstract


Introduction: Inhabitants living in areas with endemic dietary iodine intake deficiency develop nodular goitre. The aim of our study was to evaluate thyroid morphology and function among adults residing in Lower Silesia and to assess the effect on the thyroid gland of an iodine-based contrasting agent administered during a cardiac intervention procedure.
Materials and methods: The first part of the study (evaluation of thyroid gland) was carried out on 120 subjects (78 men and 42 women). From among this group, invasive cardiac procedures were performed on 60 subjects (38 men and 22 women) during the second part of the study. Endocrine tests were repeated one, three, and six months after the invasive procedure.
Results: 1) Within the studied group, pathological changes in thyroid morphology were found in 49.1%, and thyroid function disturbances in 9.3%, of all subjects. 2) A decrease in TSH concentration with a corresponding increase in fT3 concentration was seen at the second visit (four weeks after iodine administration) leading to the diagnosis of hyperthyroidism in 15% of subjects.
Conclusions: 1) Considering the multitude of silent thyroid pathologies, particular care is required before administering an iodine-based medium. 2) It is reasonable and advisable to monitor TSH and fT3 levels before and at four weeks after administration of an iodine-containing contrast agent. 3) Thyroid morphology and function disturbances after iodine administration do not necessitate treatment, as they are of transient character and only require monitoring.

Abstract


Introduction: Inhabitants living in areas with endemic dietary iodine intake deficiency develop nodular goitre. The aim of our study was to evaluate thyroid morphology and function among adults residing in Lower Silesia and to assess the effect on the thyroid gland of an iodine-based contrasting agent administered during a cardiac intervention procedure.
Materials and methods: The first part of the study (evaluation of thyroid gland) was carried out on 120 subjects (78 men and 42 women). From among this group, invasive cardiac procedures were performed on 60 subjects (38 men and 22 women) during the second part of the study. Endocrine tests were repeated one, three, and six months after the invasive procedure.
Results: 1) Within the studied group, pathological changes in thyroid morphology were found in 49.1%, and thyroid function disturbances in 9.3%, of all subjects. 2) A decrease in TSH concentration with a corresponding increase in fT3 concentration was seen at the second visit (four weeks after iodine administration) leading to the diagnosis of hyperthyroidism in 15% of subjects.
Conclusions: 1) Considering the multitude of silent thyroid pathologies, particular care is required before administering an iodine-based medium. 2) It is reasonable and advisable to monitor TSH and fT3 levels before and at four weeks after administration of an iodine-containing contrast agent. 3) Thyroid morphology and function disturbances after iodine administration do not necessitate treatment, as they are of transient character and only require monitoring.
Get Citation

Keywords

thyroid gland; nodular goitre; iodine intake deficiency; invasive cardiac procedures

About this article
Title

Comparison and assessment of thyroid morphology and function in inhabitants of Lower Silesia before and after administration of a single dose of iodine-containing contrast agent during cardiac intervention procedure

Journal

Endokrynologia Polska

Issue

Vol 63, No 4 (2012)

Pages

294-299

Published online

2012-08-30

Bibliographic record

Endokrynologia Polska 2012;63(4):294-299.

Keywords

thyroid gland
nodular goitre
iodine intake deficiency
invasive cardiac procedures

Authors

Katarzyna Skórkowska-Telichowska
Joanna Kosińska
Rafał Szymczak
Dominika Tuchendler
Renata Tuchendler
Artur Telichowski
Grzegorz Szajn
Marek Bolanowski

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