Vol 6, No 1 (2021)
Research paper
Published online: 2021-03-16

open access

Page views 632
Article views/downloads 592
Get Citation

Connect on Social Media

Connect on Social Media

Clinical utility of EDACS-ADP in patients admitted with chest pain to an emergency department

Ilker Akbas1, Zeynep Cakir2, Abdullah Osman Kocak2, Alpaslan Ünlü3, Nazim Onur Can4, Mert Vural2, Muhammed Zübeyr Köse2
Disaster Emerg Med J 2021;6(1):33-40.

Abstract

BACKGROUND: Acute coronary syndrome (ACS) is a common cause of mortality and morbidity. An ACS diagnosis can be made with electrocardiogram (ECG) and cardiac markers. However, despite medical advances, 2–5% of ACS patients are undiagnosed and discharged from emergency departments (EDs) because clinicians often find it difficult not only to diagnose and treat high-risk patients but also to define nonemergency diseases or safely discharge healthy patients. Risk stratification can be prevented, and inappropriate diagnosis and treatment protocols can be identified. The ED Assessment of Chest Pain Score-Accelerated Diagnostic Protocol (EDACS-ADP) scoring system, developed to identify patients with chest pain but at low risk for a major adverse cardiac event (MACE), is the first score based on clinical data from emergency medicine.   OBJECTIVES: This study investigates the usability of EDACS-ADP in Turkey.   MATERIALS AND METHODS: This is a prospective observational study of 392 patients. The primary outcome was a major adverse cardiovascular event (MACE) within thirty days.   RESULTS: A total of 116 MACEs occurred in 65 (16,6%) patients during a one-month follow-up. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (+ LR), and negative likelihood ratio (–LR) values of the EDACS-ADP score for the evaluation of 30-day MACE rate in patients who admitted with chest pain for two months were as follows: 96.9%, 64.5%, 35.2%, 99.1%, + LR: 2.73, and –LR: 0.05.   CONCLUSION: Most of these patients were classified by the EDACS-ADP as low risk and suitable for discharge. The 30-day MACE rate of development was significantly low (0.9%) and acceptable in patients grouped as low risk.

Article available in PDF format

View PDF Download PDF file

References

  1. Bruno RR, Donner-Banzhoff N, Söllner W, et al. The Interdisciplinary Management of Acute Chest Pain. Dtsch Arztebl Int. 2015; 112(45): 768–79; quiz 780.
  2. Almansa C, Achem S. Non-Cardiac Chest Pain of Non-Esophageal Origin. Chest Pain with Normal Coronary Arteries. 2013: 9–21.
  3. McCaig LF, Burt CW, Ly N, et al. National Hospital Ambulatory Medical Care Survey: 2000 outpatient department summary. Adv Data. 2002(327): 1–27.
  4. Gerber TC, Kontos MC, Kantor B. Emergency department assessment of acute-onset chest pain: contemporary approaches and their consequences. Mayo Clin Proc. 2010; 85(4): 309–313.
  5. Kohn MA, Kwan E, Gupta M, et al. Prevalence of acute myocardial infarction and other serious diagnoses in patients presenting to an urban emergency department with chest pain. J Emerg Med. 2005; 29(4): 383–390.
  6. Tintinalli J. Emergency Medicine: A Comprehensive Review. JAMA. 1983; 249(15): 2095.
  7. Ozturk TC, Guneysel O, Yesil O, et al. A New Approach To Chest Pain in the Emergency Room: “Triple Rule-Out CT. Journal of Academic Emergency Medicine. 2012; 11(1): 41–46.
  8. Backus BE. The HEART score for chest pain patients: Utrecht University; 2012 (Dissertation) ISBN. : 9789088914195.
  9. Huis In 't Veld MA, Cullen L, Mahler SA, et al. The Fast and the Furious: Low-Risk Chest Pain and the Rapid Rule-Out Protocol. West J Emerg Med. 2017; 18(3): 474–478.
  10. Sanders S, Flaws D, Than M, et al. Simplification of a scoring system maintained overall accuracy but decreased the proportion classified as low risk. J Clin Epidemiol. 2016; 69: 32–39.
  11. Stopyra JP, Miller CD, Hiestand BC, et al. Performance of the EDACS-accelerated Diagnostic Pathway in a Cohort of US Patients with Acute Chest Pain. Crit Pathw Cardiol. 2015; 14(4): 134–138.
  12. Than M, Flaws D, Sanders S, et al. Development and validation of the Emergency Department Assessment of Chest pain Score and 2 h accelerated diagnostic protocol. Emerg Med Australas. 2014; 26(1): 34–44.
  13. Flaws D, Than M, Scheuermeyer FX, et al. External validation of the emergency department assessment of chest pain score accelerated diagnostic pathway (EDACS-ADP). Emerg Med J. 2016; 33(9): 618–625.
  14. Than M, Herbert M, Flaws D, et al. What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the Emergency Department?: a clinical survey. Int J Cardiol. 2013; 166(3): 752–754.
  15. Roche T, Jennings N, Clifford S, et al. Review article: Diagnostic accuracy of risk stratification tools for patients with chest pain in the rural emergency department: A systematic review. Emerg Med Australas. 2016; 28(5): 511–524.
  16. SGK. Genel Sağlik Sigortasi Sistemi Nisan 2017.