open access

Vol 5, No 3 (2020)
Letter to the Editor
Published online: 2020-06-15
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Interferon lambda with remdesivir as a potential treatment option in COVID-19

Ishag Adam1, Lukasz Szarpak2, Krzysztof Jerzy Filipiak3, Jacek Smereka4, Marek Dabrowski5, Saeid Ghavami67, Milosz Jaguszewski8
DOI: 10.5603/DEMJ.a2020.0027
Disaster Emerg Med J 2020;5(3):174.


  1. Department of Obstetrics and Gynecology, Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah, Saudi Arabia
  2. Institute of Outcomes Research, Maria Sklodowska-Curie Medical Academy, Warsaw, Poland
  3. 1st Department of Cardiology, Medical University of Warsaw, Poland
  4. Wroclaw Medical University · Department of Emergency Medical Service, Parkowa Str 34, 50-365 Wroclaw, Poland
  5. Chair and Department of Medical Education, Poznan University of Medical Sciences, Poznan, Poland
  6. Research Institute in Oncology and Hematology, Cancer Care Manitoba, University of Manitoba, Winnipeg, Canada
  7. Cellular and Molecular Research Center, Department of Anatomy, Faculty of Medicine, Iran University of Medical Sciences, Tehran
  8. 1st Department of Cardiology, Medical University of Gdansk, Poland

open access

Vol 5, No 3 (2020)
Published online: 2020-06-15


Not available


Not available
Get Citation


remdesivir, interferon lambda, COVID-19, SARS-CoV-2, treatment

About this article

Interferon lambda with remdesivir as a potential treatment option in COVID-19


Disaster and Emergency Medicine Journal


Vol 5, No 3 (2020)

Article type

Letter to the Editor



Published online




Bibliographic record

Disaster Emerg Med J 2020;5(3):174.


interferon lambda


Ishag Adam
Lukasz Szarpak
Krzysztof Jerzy Filipiak
Jacek Smereka
Marek Dabrowski
Saeid Ghavami
Milosz Jaguszewski

References (5)
  1. Grein J, Ohmagari N, Shin D, et al. Compassionate Use of Remdesivir for Patients with Severe Covid-19. N Engl J Med. 2020 [Epub ahead of print].
  2. Malik YS, Sircar S, Bhat S, et al. Emerging novel coronavirus (2019-nCoV)-current scenario, evolutionary perspective based on genome analysis and recent developments. Vet Q. 2020; 40(1): 68–76.
  3. Gordon CJ, Tchesnokov EP, Woolner E, et al. Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency. J Biol Chem. 2020; 295(20): 6785–6797.
  4. Hemann EA, Schwerk J, Savan R. IFN-λ 'guts' neutrophil-mediated inflammation. Nat Immunol. 2017; 18(10): 1061–1062.
  5. Mordstein M, Neugebauer E, Ditt V, et al. Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections. J Virol. 2010; 84(11): 5670–5677.

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