Vol 5, No 3 (2020)
Letter to the Editor
Published online: 2020-06-15

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Interferon lambda with remdesivir as a potential treatment option in COVID-19

Ishag Adam1, Lukasz Szarpak2, Krzysztof Jerzy Filipiak3, Jacek Smereka4, Marek Dabrowski5, Saeid Ghavami67, Milosz Jaguszewski8
Disaster Emerg Med J 2020;5(3):174.

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References

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  3. Gordon CJ, Tchesnokov EP, Woolner E, et al. Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency. J Biol Chem. 2020; 295(20): 6785–6797.
  4. Hemann EA, Schwerk J, Savan R. IFN-λ 'guts' neutrophil-mediated inflammation. Nat Immunol. 2017; 18(10): 1061–1062.
  5. Mordstein M, Neugebauer E, Ditt V, et al. Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections. J Virol. 2010; 84(11): 5670–5677.