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The value of carotid intima-media measurements during the periods of attack and remission of migraine disease and tension-type headache in differential diagnosis
, 2, 3, 4, 2, 2, 5, 6
Affiliations- Department of Emergency Medicine, University of Health Sciences, Ankara Training and Research Hospital, Ankara, Turkey
- Department of Emergency Medicine, Ufuk University, Faculty of Medicine, Ankara, Turkey
- Department of Neurology, Ufuk University, Faculty of Medicine, Ankara, Turkey
- Department of Radiology, Ufuk University, Faculty of Medicine, Ankara, Turkey
- Department of Emergency Medicine, University of Health Sciences, İstanbul Kartal Dr Lütfi Kırdar Training and Research Hospital, İstanbul, Turkey
- Institute of Outcomes Research, Maria Sklodowska-Curie Medical Academy, Warsaw, Poland
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Abstract
INTRODUCTION: In Turkey, 2% of emergency department admissions are migraine and there is no specific biomarker with differential diagnostic value in patients presenting with headache. There are studies showing that the blood-brain barrier deteriorates during migraine attacks, the risk of atherosclerosis is increased in migraine patients and it is associated with cardiovascular and cerebrovascular diseases. In light of this information, the value of carotid intima-media thickness (CIMT) measurements in the differential diagnosis of tension and migraine headache was investigated.
MATERIAL AND METHODS: The study group consisting of 20 tension headache, 23 migraine attacks, 20 remission migraine patients admitted to the emergency department and neurology outpatient clinic of Ridvan Ege Hospital between February and September 2017 and control group of 21 healthy volunteers were compared. Carotid intima-media thickness (CIMT) of all participants was measured by specialist radiologist. The data obtained were analysed using SPSS 15.0 statistical program.
RESULTS: There was no significant difference between the participants in terms of age and gender. When the carotid intima-media thickness was analysed between the four groups and according to the presence and type of migraine, no significant difference was found (p = 0.489).
CONCLUSIONS: This is the first study in the literature which evaluates the relationship between subclinical atherosclerosis and tension-type headache and migraine by examining patients with tension-type headache and migraine disease in both episode and remission period. According to the results obtained, migraine and tension headache is not associated with subclinical atherosclerosis. However, larger-scale studies are required in this sense.
Abstract
INTRODUCTION: In Turkey, 2% of emergency department admissions are migraine and there is no specific biomarker with differential diagnostic value in patients presenting with headache. There are studies showing that the blood-brain barrier deteriorates during migraine attacks, the risk of atherosclerosis is increased in migraine patients and it is associated with cardiovascular and cerebrovascular diseases. In light of this information, the value of carotid intima-media thickness (CIMT) measurements in the differential diagnosis of tension and migraine headache was investigated.
MATERIAL AND METHODS: The study group consisting of 20 tension headache, 23 migraine attacks, 20 remission migraine patients admitted to the emergency department and neurology outpatient clinic of Ridvan Ege Hospital between February and September 2017 and control group of 21 healthy volunteers were compared. Carotid intima-media thickness (CIMT) of all participants was measured by specialist radiologist. The data obtained were analysed using SPSS 15.0 statistical program.
RESULTS: There was no significant difference between the participants in terms of age and gender. When the carotid intima-media thickness was analysed between the four groups and according to the presence and type of migraine, no significant difference was found (p = 0.489).
CONCLUSIONS: This is the first study in the literature which evaluates the relationship between subclinical atherosclerosis and tension-type headache and migraine by examining patients with tension-type headache and migraine disease in both episode and remission period. According to the results obtained, migraine and tension headache is not associated with subclinical atherosclerosis. However, larger-scale studies are required in this sense.
Keywords
migraine; tension-type headache; carotid intima-media thickness; emergency medicine
About this articleTitle
The value of carotid intima-media measurements during the periods of attack and remission of migraine disease and tension-type headache in differential diagnosis
Journal
Disaster and Emergency Medicine Journal
Issue
Article type
Research paper
Pages
109-115
Published online
2019-10-08
Page views
576
Article views/downloads
578
DOI
Bibliographic record
Disaster Emerg Med J 2019;4(3):109-115.
Keywords
migraine
tension-type headache
carotid intima-media thickness
emergency medicine
Authors
Gülden Kazancı
Togay Evrin
Burak Katipoğlu
Refah Sayın
Ebru Özan Sanhal
Ertuğrul Kazancı
Fatih Demir
Semih Korkut
Lukasz Szarpak
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