Tom 15, Nr 4 (2018)
Nadciśnienie tętnicze
Opublikowany online: 2018-12-13
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Obturacyjny bezdech senny i jego związek z nadciśnieniem tętniczym — wciąż aktualny temat
Choroby Serca i Naczyń 2018;15(4):226-231.
Streszczenie
Obturacyjny bezdech senny (OSA) jest chorobą zaliczaną do zaburzeń oddychania w trakcie snu. W wyniku obturacji górnych dróg oddechowych dochodzi do okresów przemijającego spłycenia oddechu lub całkowitych bezdechów. W następstwie powtarzającej się hipoksji dochodzi do pobudzenia układu współczulnego, upośledzenia funkcji śródbłonka oraz aktywacji układu renina–angiotensyna–aldosteron. Konsekwencją tego jest rozwój nadciśnienia tętniczego, które występuje u ponad 50% chorych na OSA. W leczeniu nadciśnienia tętniczego związanego z OSA duże znaczenie ma terapia z użyciem ciągłego dodatniego ciśnienia w drogach oddechowych (CPAP). W przypadku nadciśnienia lekoopornego zastosowanie znajduje denerwacja tętnic nerkowych.
Słowa kluczowe: obturacyjny bezdech senny (OSA)nadciśnienie tętniczeCPAPdenerwacja tętnic nerkowych
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