Zaburzenia rytmu serca u kobiet
Streszczenie
Odmienności nadkomorowych i komorowych zaburzeń rytmu serca u kobiet i mężczyzn są od dawna powszechnie znane. Obserwacje kliniczne pozwoliły wyciągnąć wnioski o przewadze występowania niektórych ich rodzajów u kobiet. Wynika to z zależnych od płci różnic w parametrach elektrofizjologicznych, których przyczyny nie są dokładnie poznane. Upatruje się je we właściwościach samego węzła zatokowego, w różnej spoczynkowej czynności serca, ekspresji i w rozmieszczeniu podjednostek kanałów jonowych w sercu, a także we wpływie hormonów płciowych u kobiet. Różnice te powodują odmienności w zależności od płci w częstości występowania arytmii, jej przebiegu klinicznym, odpowiedzi na leczenie oraz rokowaniu. Dotyczy to zarówno nadkomorowych, jak i komorowych zaburzeń rytmu serca. Zaburzenia rytmu i przewodzenia u kobiet częściej występują pod postacią choroby węzła zatokowego w porównaniu z zaburzeniami przewodnictwa przedsionkowo-komorowego, które przeważają u mężczyzn. W pracy zwrócono uwagę na zaburzenia rytmu częściej występujące u kobiet, szukano odpowiedzi, dlaczego tak się dzieje, a także jak to wpływa na rokowanie odległe.
Słowa kluczowe: płeć żeńskaarytmiechoroba węzła zatokowegozaburzenia przewodzenia przedsionkowo-komorowego
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