Tom 13, Nr 6 (2016)
Z pogranicza kardiologii
Opublikowany online: 2017-04-06
Wyświetlenia strony
2185
Wyświetlenia/pobrania artykułu
10138
Kardiotoksyczność leczenia przeciwnowotworowego
Choroby Serca i Naczyń 2016;13(6):434-444.
Streszczenie
Kardiotoksyczność chemioterapii lub radioterapii ma istotny wpływ na jakość życia oraz przedwczesny zgon pacjentów onkologicznych. Pacjenci przyjmujący chemioterapię stanowią grupę podwyższonego ryzyka zdarzeń sercowych — wśród nich najczęściej pojawiającym się powikłaniem jest dysfunkcja lewej komory z niewydolnością serca lub bez niej. W zależności od zastosowanej terapii toksyczność ta może być przemijająca lub trwała. Najlepiej poznane są powikłania kardiologiczne indukowane antracyklinami i trastuzumabem, lecz ich diagnostyka, prewencja i leczenie pozostają przedmiotem dalszych badań. W niniejszej pracy przedstawiono aktualny stan wiedzy dotyczący definicji, czynników ryzyka oraz diagnostyki powikłań kardiologicznych terapii przeciwnowotworowej.
Słowa kluczowe: kardiotoksycznośćleczenie przeciwnowotworowediagnostyka kardiotoksyczności
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