open access

Vol 26, No 1 (2022)
Original paper
Published online: 2022-03-28
Get Citation

Early detecting myocardial entity damage using 2D speckle tracking echocardiography through strain parameters in hypertensive patients

Thị Nguyễn Diễm1, Vũ Anh Nguyễn2, Lợi Doãn Đỗ3, Nhân Hữu Kha1, An Viết Trần1, Quốc Lâm Thiện Huỳnh1, Bảo Lâm Thái Trần1, Quan Nhất Kỳ Nguyễn1
DOI: 10.5603/AH.a2022.0001
·
Arterial Hypertension 2022;26(1):15-25.
Affiliations
  1. Can Tho University of Medicine and Pharmacy, Can Tho, Viet Nam
  2. Hue University of Medicine and Pharmacy, Hue, Viet Nam
  3. Hanoi Medical University, Hanoi, Hanoi, Viet Nam

open access

Vol 26, No 1 (2022)
ORIGINAL PAPERS
Published online: 2022-03-28

Abstract

Background: The prevalence of hypertension in Vietnam is increasing consecutively. Hypertension is the cause of many complications in several vital systems such as the nervous system, kidney and, especially, the cardiovascular system. Recently, the 2D speckle tracking echocardiography (STE) technique helped to assess subclinical changes in cardiac function when there was an abnormal tissue function without any changes in morphology and cardiac function.

The aim of the study was to evaluate the early change in left ventricular systolic function by STE technique in hypertensive patients with and without heart failure with preserved ejection fraction (HFpEF).

Material and methods: In a cross-sectional observational study, STE technique was used to analyze left ventricular systolic strain in 151 hypertensive patients and 43 participants without cardiovascular disease as a control group. Subclinical left ventricular dysfunction was detected by echocardiographic strain parameters, especially global longitudinal strain (GLS).

Results: GLS decreased in hypertensive patients without heart failure with preserved ejection fraction compared to the control group (–11.93 ± 2.21 vs. –16.52 ± 1.19). This reduction increased in hypertensive patients with heart failure with preserved ejection fraction (–11.04 ± 2.5 vs. –16.52 ± 1.19). The threshold of the global longitudinal strain was –14.364. The rate of reduction in GLS in hypertensive patients without HFpEF was relatively high (93.3%).

Conclusion: STE technique helps to detect subclinical changes in left ventricular systolic function with high sensitivity.

Abstract

Background: The prevalence of hypertension in Vietnam is increasing consecutively. Hypertension is the cause of many complications in several vital systems such as the nervous system, kidney and, especially, the cardiovascular system. Recently, the 2D speckle tracking echocardiography (STE) technique helped to assess subclinical changes in cardiac function when there was an abnormal tissue function without any changes in morphology and cardiac function.

The aim of the study was to evaluate the early change in left ventricular systolic function by STE technique in hypertensive patients with and without heart failure with preserved ejection fraction (HFpEF).

Material and methods: In a cross-sectional observational study, STE technique was used to analyze left ventricular systolic strain in 151 hypertensive patients and 43 participants without cardiovascular disease as a control group. Subclinical left ventricular dysfunction was detected by echocardiographic strain parameters, especially global longitudinal strain (GLS).

Results: GLS decreased in hypertensive patients without heart failure with preserved ejection fraction compared to the control group (–11.93 ± 2.21 vs. –16.52 ± 1.19). This reduction increased in hypertensive patients with heart failure with preserved ejection fraction (–11.04 ± 2.5 vs. –16.52 ± 1.19). The threshold of the global longitudinal strain was –14.364. The rate of reduction in GLS in hypertensive patients without HFpEF was relatively high (93.3%).

Conclusion: STE technique helps to detect subclinical changes in left ventricular systolic function with high sensitivity.

Get Citation

Keywords

speckle tracking echocardiography; systolic function; strain parameters; hypertension; heart failure with preserved ejection fraction; Vietnam

About this article
Title

Early detecting myocardial entity damage using 2D speckle tracking echocardiography through strain parameters in hypertensive patients

Journal

Arterial Hypertension

Issue

Vol 26, No 1 (2022)

Article type

Original paper

Pages

15-25

Published online

2022-03-28

Page views

236

Article views/downloads

42

DOI

10.5603/AH.a2022.0001

Bibliographic record

Arterial Hypertension 2022;26(1):15-25.

Keywords

speckle tracking echocardiography
systolic function
strain parameters
hypertension
heart failure with preserved ejection fraction
Vietnam

Authors

Thị Nguyễn Diễm
Vũ Anh Nguyễn
Lợi Doãn Đỗ
Nhân Hữu Kha
An Viết Trần
Quốc Lâm Thiện Huỳnh
Bảo Lâm Thái Trần
Quan Nhất Kỳ Nguyễn

References (26)
  1. Magyar K. From hypertension to heart failure. World J Hypertens. 2015; 5(2): 85.
  2. Son PT, Quang NN, Viet NL, et al. Prevalence, awareness, treatment and control of hypertension in Vietnam-results from a national survey. J Hum Hypertens. 2012; 26(4): 268–280.
  3. Shahul S, Rhee J, Hacker MR, et al. Subclinical left ventricular dysfunction in preeclamptic women with preserved left ventricular ejection fraction: a 2D speckle-tracking imaging study. Circ Cardiovasc Imaging. 2012; 5(6): 734–739.
  4. Mizuguchi Y, Oishi Y, Miyoshi H, et al. Concentric left ventricular hypertrophy brings deterioration of systolic longitudinal, circumferential, and radial myocardial deformation in hypertensive patients with preserved left ventricular pump function. J Cardiol. 2010; 55(1): 23–33.
  5. Gonçalves S, Cortez-Dias N, Nunes A, et al. Left ventricular systolic dysfunction detected by speckle tracking in hypertensive patients with preserved ejection fraction. Rev Port Cardiol. 2014; 33(1): 27–37.
  6. Voigt JU, Pedrizzetti G, Lysyansky P, et al. Definitions for a common standard for 2D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. Eur Heart J Cardiovasc Imaging. 2015; 16(1): 1–11.
  7. Maharaj N, Peters F, Khandheria BK, et al. Left ventricular twist in a normal African adult population. Eur Heart J Cardiovasc Imaging. 2013; 14(6): 526–533.
  8. Morris DA, Otani K, Bekfani T, et al. Multidirectional global left ventricular systolic function in normal subjects and patients with hypertension: multicenter evaluation. J Am Soc Echocardiogr. 2014; 27(5): 493–500.
  9. Morris DA, Boldt LH, Eichstädt H, et al. Myocardial systolic and diastolic performance derived by 2-dimensional speckle tracking echocardiography in heart failure with normal left ventricular ejection fraction. Circ Heart Fail. 2012; 5(5): 610–620.
  10. Kraigher-Krainer E, Shah AM, Gupta DK, et al. PARAMOUNT Investigators. Impaired systolic function by strain imaging in heart failure with preserved ejection fraction. J Am Coll Cardiol. 2014; 63(5): 447–456.
  11. Brilla CG, Janicki JS, Weber KT. Impaired diastolic function and coronary reserve in genetic hypertension. Role of interstitial fibrosis and medial thickening of intramyocardial coronary arteries. Circ Res. 1991; 69(1): 107–115.
  12. Galderisi M, Lomoriello VS, Santoro A, et al. Differences of myocardial systolic deformation and correlates of diastolic function in competitive rowers and young hypertensives: a speckle-tracking echocardiography study. J Am Soc Echocardiogr. 2010; 23(11): 1190–1198.
  13. Kosmala W, Plaksej R, Strotmann JM, et al. Progression of left ventricular functional abnormalities in hypertensive patients with heart failure: an ultrasonic two-dimensional speckle tracking study. J Am Soc Echocardiogr. 2008; 21(12): 1309–1317.
  14. Imbalzano E, Zito C, Carerj S, et al. Left ventricular function in hypertension: new insight by speckle tracking echocardiography. Echocardiography. 2011; 28(6): 649–657.
  15. Ma C, Chen J, Yang J, et al. Quantitative assessment of left ventricular function by 3-dimensional speckle-tracking echocardiography in patients with chronic heart failure: a meta-analysis. J Ultrasound Med. 2014; 33(2): 287–295.
  16. Kouzu H, Yuda S, Muranaka A, et al. Left ventricular hypertrophy causes different changes in longitudinal, radial, and circumferential mechanics in patients with hypertension: a two-dimensional speckle tracking study. J Am Soc Echocardiogr. 2011; 24(2): 192–199.
  17. Phan TT, Shivu GN, Abozguia K, et al. Left ventricular torsion and strain patterns in heart failure with normal ejection fraction are similar to age-related changes. Eur J Echocardiogr. 2009; 10(6): 793–800.
  18. Wang J, Khoury DS, Yue Y, et al. Preserved left ventricular twist and circumferential deformation, but depressed longitudinal and radial deformation in patients with diastolic heart failure. Eur Heart J. 2008; 29(10): 1283–1289.
  19. Ahmed MI, Desai RV, Gaddam KK, et al. Relation of torsion and myocardial strains to LV ejection fraction in hypertension. JACC Cardiovasc Imaging. 2012; 5(3): 273–281.
  20. Ta CM. Study on S/D ratio and Tei index in assessing whole ventricular function in hypertensive patients by Doppler echocardiography. Vietnam Med J. 2012; 2: 92–97.
  21. Amundsen B, Helle-Valle T, Edvardsen T, et al. Noninvasive Myocardial Strain Measurement by Speckle Tracking Echocardiography. J Am Coll Cardiol. 2006; 47(4): 789–793.
  22. Stoylen A. Strain rate imaging, Cardiac deformation imaging by ultrasound/echocardiography — Tissue Doppler and Speckle tracking. Norwegian University of Science and Technology, Oslo 2008: 1–70.
  23. Nguyen DT, Nguyen VA, Do LD. Initial application of tissue markers in the assessment of left ventricular ejection fraction and volume. J Vietnam Cardiol. 2013; 65: 432–435.
  24. Galderisi M, Esposito R, Schiano-Lomoriello V, et al. Correlates of global area strain in native hypertensive patients: a three-dimensional speckle-tracking echocardiography study. Eur Heart J Cardiovasc Imaging. 2012; 13(9): 730–738.
  25. Sitia S, Tomasoni L, Turiel M. Speckle tracking echocardiography: A new approach to myocardial function. World J Cardiol. 2010; 2(1): 1–5.
  26. Park SJ, Miyazaki C, Bruce CJ, et al. Left ventricular torsion by two-dimensional speckle tracking echocardiography in patients with diastolic dysfunction and normal ejection fraction. J Am Soc Echocardiogr. 2008; 21(10): 1129–1137.

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl