open access
Aortic knob width is associated with non-dipping blood pressure pattern


- Department of Radiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey
- Department of Cardiology, Istanbul Education and Research Hospital, Saglik Bilimleri Universitesi, Istanbul, Turkey
- Department of Cardiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey
open access
Abstract
Background: Aortic knob width (AKW) is the measurement of the radiographic configuration composed of the foreshortened aortic arch and a part of the descending aorta. We investigated the relationship between the nondipper pattern and AKW.
Material and methods: All patients’ office blood pressure measurements and 24-hour ambulatory blood pressure readings were recorded. A blood pressure drop of less than 10% was defined as non-dipping. The patients were grouped into Group 1; dipper pattern (37 patients; 22F, and mean age 49.2 ± 11.7 yrs) and Group 2; non-dipper pattern (64 patients; 37F, and mean age 53.7 ± 13.1 yrs). On posteroanterior chest radiography, the widest point of the aortic knob was measured along the straight imaginary line from the lateral edge of the trachea to the left lateral wall of the aortic arch.
Results: AKW was significantly higher in Group 2 compared to group 1 (36.7 ± 5.7 vs. 30.7 ± 4.5 mm, p < 0.001). The mean daytime and night-time systolic blood pressures, the mean night-time diastolic blood pressure levels, 24-hour mean blood pressure and mean pulse pressures were higher; percentage of nocturnal drops was significantly lower in Group 2 compared to Group 1. AKW was determined to be the parameter that was mostly related to the non-dipper pattern. A ROC analysis revealed that the area under the curve values for AKW values of non-dippers were 0.796 (95% CI: 0.707–0.884, p < 0.001).
Conclusion: AKW is significantly higher in non-dipper individuals compared to dippers. AKW values above
32.6 mm on the chest radiograph may be associated with non-dipper pattern especially in hypertensive individuals.
Abstract
Background: Aortic knob width (AKW) is the measurement of the radiographic configuration composed of the foreshortened aortic arch and a part of the descending aorta. We investigated the relationship between the nondipper pattern and AKW.
Material and methods: All patients’ office blood pressure measurements and 24-hour ambulatory blood pressure readings were recorded. A blood pressure drop of less than 10% was defined as non-dipping. The patients were grouped into Group 1; dipper pattern (37 patients; 22F, and mean age 49.2 ± 11.7 yrs) and Group 2; non-dipper pattern (64 patients; 37F, and mean age 53.7 ± 13.1 yrs). On posteroanterior chest radiography, the widest point of the aortic knob was measured along the straight imaginary line from the lateral edge of the trachea to the left lateral wall of the aortic arch.
Results: AKW was significantly higher in Group 2 compared to group 1 (36.7 ± 5.7 vs. 30.7 ± 4.5 mm, p < 0.001). The mean daytime and night-time systolic blood pressures, the mean night-time diastolic blood pressure levels, 24-hour mean blood pressure and mean pulse pressures were higher; percentage of nocturnal drops was significantly lower in Group 2 compared to Group 1. AKW was determined to be the parameter that was mostly related to the non-dipper pattern. A ROC analysis revealed that the area under the curve values for AKW values of non-dippers were 0.796 (95% CI: 0.707–0.884, p < 0.001).
Conclusion: AKW is significantly higher in non-dipper individuals compared to dippers. AKW values above
32.6 mm on the chest radiograph may be associated with non-dipper pattern especially in hypertensive individuals.
Keywords
aortic knob width; non-dipper pattern; hypertension; chest radiography


Title
Aortic knob width is associated with non-dipping blood pressure pattern
Journal
Issue
Article type
Original paper
Pages
145-151
Published online
2021-08-19
Page views
3115
Article views/downloads
119
DOI
10.5603/AH.a2021.0023
Bibliographic record
Arterial Hypertension 2021;25(4):145-151.
Keywords
aortic knob width
non-dipper pattern
hypertension
chest radiography
Authors
Fuldem Mutlu
Suleyman Cagan Efe
Ibrahim Kocayigit
Ahmet Oz
Turgut Karabag


- Kannel W. Blood Pressure as a Cardiovascular Risk Factor. JAMA. 1996; 275(20): 1571.
- Pickering TG. The clinical significance of diurnal blood pressure variations. Dippers and nondippers. Circulation. 1990; 81(2): 700–702.
- O'Brien E, Sheridan J, O'Malley K. Dippers and non-dippers. Lancet. 1988; 332(8607): 397.
- Birkenhäger AM, van den Meiracker AH. Causes and consequences of a non-dipping blood pressure profile. . Neth J Med. 2007; 65(4): 127–131.
- Rayner BL, Goodman H, Opie LH. The chest radiograph. A useful investigation in the evaluation of hypertensive patients. Am J Hypertens. 2004; 17(6): 507–510.
- Erkan H, Korkmaz L, Ağaç MT, et al. Relation between carotid intima-media thickness and aortic knob width in patients with essential hypertension. Blood Press Monit. 2011; 16(6): 282–284.
- Korkmaz L, Erkan H, Korkmaz AA, et al. Relationship of aortic knob width with cardio-ankle vascular stiffness index and its value in diagnosis of subclinical atherosclerosis in hypertensive patients: a study on diagnostic accuracy. Anadolu Kardiyol Derg. 2012; 12(2): 102–106.
- Gürbak İ, Yıldız İ, Panç C. Relation between aortic knob width and subclinical left ventricular dysfunction in hypertensive patients. Clin Exp Hypertens. 2018; 40(6): 589–594.
- orld Health Organization. Obesity: Prevention and Managing the Global Epidemic. WHO Obesity Technical Reports Series 894. WHO, Geneva 2000. https://www.who.int/nutrition/publications/obesity/WHO_TRS_894/en/.
- Grundy SM, Cleeman JI, Daniels SR, et al. American Heart Association, National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005; 112(17): 2735–2752.
- Lee EJ, Han JH, Kwon KY, et al. The Relationship between Aortic Knob Width and Metabolic Syndrome. Korean J Fam Med. 2018; 39(4): 253–259.
- Williams B, Mancia G, Spiering W, et al. ESC Scientific Document Group . 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018; 39(33): 3021–3104.
- Tykarski A, Filipiak K, Januszewicz A, et al. 2019 Guidelines for the Management of Hypertension — Part 1–7. Arterial Hypertension. 2019; 23(2): 41–87.
- Lang RM, Badano LP, Mor-Avi V, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015; 28(1): 1–39.e14.
- Yun KHo, Jeong MHo, Oh SK, et al. Clinical significance of aortic knob width and calcification in unstable angina. Circ J. 2006; 70(10): 1280–1283.
- Sung SY, Han JH, Kim JH, et al. The Relationship between Heart Rate Variability and Aortic Knob Width. Korean J Fam Med. 2019; 40(1): 39–44.
- Jeon WK, Kim MA, Kim HL, et al. Association between aortic knob width and invasively measured aortic pulse pressure. Blood Press Monit. 2018; 23(3): 121–126.
- Sevencan NO, Ozkan AE. Renal resistive index and aortic knob width relationship as a predictor of renal prognosis in essential hypertension. Medicine (Baltimore). 2018; 97(40): e12434.