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Original paper
Published online: 2021-08-19
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Assessment of atherogenic indices and lipid ratios in the apparently healthy women aged 30-55 years

Roghayeh Molani Gol1, Maryam Rafraf2, Mohammad Asghari Jafarabadi3
DOI: 10.5603/AH.a2021.0020
Affiliations
  1. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
  2. Nutrition Research Center, Department of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran.
  3. Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

open access

Ahead of print
ORIGINAL PAPERS
Published online: 2021-08-19

Abstract

Background: Cardiovascular disease (CVD) is the main cause of death worldwide and atherogenic dyslipidemia is an established risk factor for CVD. This cross-sectional study aimed to assess the atherogenic indices and lipid ratios including atherogenic coefficient (AC), atherogenic index of plasma (AIP), cholindex (CI), castelli risk index-1 (CRI-1), CRI-2, and non-HDL-C in women living in the Tabriz, Iran during April – May 2017. Material and Methods: Anthropometric measurements, fasting serum lipids, and blood pressure of 150 women aged 30-55 years in Tabriz, Iran was evaluated. The atherogenic indices were calculated by the established formulas. Results: The prevalence of high AIP, AC, CI, CRI-1, CRI-2 and non-HDL-C ratios were 64.5%, 36.2%, 20.4%, 77%, 7.2% and 44.7%, respectively. In the multiple-adjusted quantile regression analysis, significant relationships were found between CI ratio and diastolic blood pressure (DBP) (B = 3.76, P = 0.035) and between CRI-2 ratio with DBP (B = 0.005, P = 0.042) and age (B = 0.005, P = 0.031). Conclusions: This study indicated that the majority of studied women had a high risk of CVD based on atherogenic indices. Further public health efforts are required to enhance awareness of women and healthcare providers about preventing and controlling CVD risk.

Abstract

Background: Cardiovascular disease (CVD) is the main cause of death worldwide and atherogenic dyslipidemia is an established risk factor for CVD. This cross-sectional study aimed to assess the atherogenic indices and lipid ratios including atherogenic coefficient (AC), atherogenic index of plasma (AIP), cholindex (CI), castelli risk index-1 (CRI-1), CRI-2, and non-HDL-C in women living in the Tabriz, Iran during April – May 2017. Material and Methods: Anthropometric measurements, fasting serum lipids, and blood pressure of 150 women aged 30-55 years in Tabriz, Iran was evaluated. The atherogenic indices were calculated by the established formulas. Results: The prevalence of high AIP, AC, CI, CRI-1, CRI-2 and non-HDL-C ratios were 64.5%, 36.2%, 20.4%, 77%, 7.2% and 44.7%, respectively. In the multiple-adjusted quantile regression analysis, significant relationships were found between CI ratio and diastolic blood pressure (DBP) (B = 3.76, P = 0.035) and between CRI-2 ratio with DBP (B = 0.005, P = 0.042) and age (B = 0.005, P = 0.031). Conclusions: This study indicated that the majority of studied women had a high risk of CVD based on atherogenic indices. Further public health efforts are required to enhance awareness of women and healthcare providers about preventing and controlling CVD risk.

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Keywords

Atherogenic indices, Lipid ratios, Dyslipidemia, Cardiovascular risk factors, Women

About this article
Title

Assessment of atherogenic indices and lipid ratios in the apparently healthy women aged 30-55 years

Journal

Arterial Hypertension

Issue

Ahead of print

Article type

Original paper

Published online

2021-08-19

DOI

10.5603/AH.a2021.0020

Keywords

Atherogenic indices
Lipid ratios
Dyslipidemia
Cardiovascular risk factors
Women

Authors

Roghayeh Molani Gol
Maryam Rafraf
Mohammad Asghari Jafarabadi

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