open access

Vol 24, No 2 (2020)
REVIEW
Published online: 2020-05-29
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The eye — a window to cardiovascular diseases

Edyta E. Dąbrowska, Joanna M. Harazny, Jacek Wolf, Urszula Szulc, Krzysztof Narkiewicz
DOI: 10.5603/AH.a2020.0006
·
Arterial Hypertension 2020;24(2):56-60.

open access

Vol 24, No 2 (2020)
REVIEW
Published online: 2020-05-29

Abstract

Microvascular alterations can parallel and even precede development of cardiovascular disease. Ocular bulb, due to transparent anatomical elements provides a unique opportunity to examine microcirculation non-invasively and in vivo by means of scanning laser Doppler flowmetry. This device enables to obtain both structural and functional parameters of retinal microvasculature. Alterations observed in retinal arterioles, i.e. lumen narrowing, increased wall-to-lumen ratio, rarefaction or reduced retinal capillary flow, have been independently associated with cardiometabolic diseases: hypertension, heart failure, coronary artery disease, stroke, chronic kidney disease and diabetes.
Therefore, examination of easily accessible retinal microcirculation may provide novel insights into the mechanisms underlying various diseases, serve as a marker of target organ damage and add valuable information to cardiovascular
risk stratification.

Abstract

Microvascular alterations can parallel and even precede development of cardiovascular disease. Ocular bulb, due to transparent anatomical elements provides a unique opportunity to examine microcirculation non-invasively and in vivo by means of scanning laser Doppler flowmetry. This device enables to obtain both structural and functional parameters of retinal microvasculature. Alterations observed in retinal arterioles, i.e. lumen narrowing, increased wall-to-lumen ratio, rarefaction or reduced retinal capillary flow, have been independently associated with cardiometabolic diseases: hypertension, heart failure, coronary artery disease, stroke, chronic kidney disease and diabetes.
Therefore, examination of easily accessible retinal microcirculation may provide novel insights into the mechanisms underlying various diseases, serve as a marker of target organ damage and add valuable information to cardiovascular
risk stratification.

Get Citation

Keywords

microcirculation; retinal arterioles; remodeling

About this article
Title

The eye — a window to cardiovascular diseases

Journal

Arterial Hypertension

Issue

Vol 24, No 2 (2020)

Pages

56-60

Published online

2020-05-29

DOI

10.5603/AH.a2020.0006

Bibliographic record

Arterial Hypertension 2020;24(2):56-60.

Keywords

microcirculation
retinal arterioles
remodeling

Authors

Edyta E. Dąbrowska
Joanna M. Harazny
Jacek Wolf
Urszula Szulc
Krzysztof Narkiewicz

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