open access
Is hypertension associated with a greater increase in creatine kinase activity following cycling exercise? A case study
Affiliations- Universidade Iguaçu at Itaperuna, 28300-000 Itaperuna, Brazil
- Centrolab, 28300-000 Itaperuna, Brazil
- State University of Southwest Bahia, Rua Jose Moreira Sobrinho, 45210-506 Jequie, Brazil
- Lenoir-Rhyne University, Hickory, United States
- Universitary Fundation of Itaperuna, 28300-000 Itaperuna, Brazil
open access
Abstract
We describe discrepant behavior of serum creatine kinase (CK) activity during and after cycling in a hypertensive athlete when compared to the healthy athletes from the same team of endurance cyclists. Heart Rate (HR), Blood Pressure (BP), Perceived Exertion (PE) and serum CK activity were evaluated before, during and after 150 km indoor cycling. The results showed that there were no differences between the hypertensive athlete and the healthy athletes in time trial (186.3 min vs. 179.1 ± 14.9 min), HR (159.3 ± 11.4 bpm vs. 169.5 ± 7.8 bpm respectively) and PE (6.3 ± 1.5 vs. 6.3 ± 1.3). Systolic BP was higher in hypertensive athlete before, during and after the exercise. Serum CK activity was higher (+47%) at baseline and exhibited a higher increase (> +200%) after exercise. Our finding shed light on a hypothesis regarding the interindividual variability of serum CK activity and its possible interaction with hypertension.
Abstract
We describe discrepant behavior of serum creatine kinase (CK) activity during and after cycling in a hypertensive athlete when compared to the healthy athletes from the same team of endurance cyclists. Heart Rate (HR), Blood Pressure (BP), Perceived Exertion (PE) and serum CK activity were evaluated before, during and after 150 km indoor cycling. The results showed that there were no differences between the hypertensive athlete and the healthy athletes in time trial (186.3 min vs. 179.1 ± 14.9 min), HR (159.3 ± 11.4 bpm vs. 169.5 ± 7.8 bpm respectively) and PE (6.3 ± 1.5 vs. 6.3 ± 1.3). Systolic BP was higher in hypertensive athlete before, during and after the exercise. Serum CK activity was higher (+47%) at baseline and exhibited a higher increase (> +200%) after exercise. Our finding shed light on a hypothesis regarding the interindividual variability of serum CK activity and its possible interaction with hypertension.
Keywords
blood pressure, creatine kinase, muscle damage, endurance
About this articleTitle
Is hypertension associated with a greater increase in creatine kinase activity following cycling exercise? A case study
Journal
Issue
Article type
Case report
Pages
104-106
Published online
2018-05-30
Page views
1443
Article views/downloads
955
DOI
Bibliographic record
Arterial Hypertension 2018;22(2):104-106.
Keywords
blood pressure
creatine kinase
muscle damage
endurance
Authors
Debora Henriques
Ester Tebaldi
Tamires Coelho
Alvaro Dutra
Rafael Pereira
Alexander J Koch
Marco Machado
References (7)- Brewster LM, Mairuhu G, Bindraban NR, et al. Creatine kinase activity is associated with blood pressure. Circulation. 2006; 114(19): 2034–2039.
- Brewster LM, Stronks K, Zwinderman AH, et al. Creatine kinase and the correlates of blood pressure in a random population sample. Hypertension. 2008; 51(1): e4–e5.
- Mougios V. Reference intervals for serum creatine kinase in athletes. Br J Sports Med. 2007; 41(10): 674–678.
- Borg G. Borg's Perceived Exertion and Pain Scales. Human Kinetics, Champaign. ; 1998.
- Sayers SP, Clarkson PM. Short-term immobilization after eccentric exercise. Part II: creatine kinase and myoglobin. Med Sci Sports Exerc. 2003; 35(5): 762–768.
- Valenzuela-Rendon J, Manning RD. Chronic lymph flow and transcapillary fluid flux during angiotensin II hypertension. Am J Physiol. 1990; 259(6 Pt 2): R1205–R1213.
- Paulus BM, Ali S, Zia AA, et al. Causes and consequences of systemic venous hypertension. Am J Med Sci. 2008; 336(6): 489–497.