Vol 25, No 4 (2021)
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Published online: 2021-08-19

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Assessment of atherogenic indices and lipid ratios in the apparently healthy women aged 30–55 years

Roghayeh Molani Gol12, Maryam Rafraf2, Mohammad Asghari Jafarabadi3
Arterial Hypertension 2021;25(4):172-177.

Abstract

Background: Cardiovascular disease (CVD) is the main cause of death worldwide and atherogenic dyslipidemia is an established risk factor for CVD. This cross-sectional study aimed to assess the atherogenic indices and lipid ratios, including atherogenic coefficient (AC), atherogenic index of plasma (AIP), cholindex (CI), Castelli risk index-1 (CRI-1), CRI-2, and non-HDL-C, in women living in the Tabriz, Iran during April–May 2017.

Material and methods: Anthropometric measurements, fasting serum lipids, and blood pressure of 150 women aged 30–55 years in Tabriz, Iran was evaluated. The atherogenic indices were calculated by the established formulas.

Results: The prevalence of high AIP, AC, CI, CRI-1, CRI-2 and non-HDL-C ratios were 64.5%, 36.2%, 20.4%, 77%, 7.2% and 44.7%, respectively. In the multiple-adjusted quantile regression analysis, significant relationships were found between CI ratio and diastolic blood pressure (DBP) (B = 3.76, p = 0.035) and between CRI-2 ratio and DBP (B = 0.005, p = 0.042) and age (B = 0.005, p = 0.031).

Conclusions: This study indicated that the majority of studied women had a high risk of CVD based on atherogenic indices. Further public health efforts are required to enhance awareness of women and healthcare providers about preventing and controlling CVD risk.

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