open access

Vol 16, No 6 (2012)
Prace oryginalne
Published online: 2013-04-12
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Assessment of the improvement in treatment efficacy and compliance in patients with arterial hypertension treated with antihypertensive drug combinations

Joanna Dziwura-Ogonowska, Tomasz Miazgowski, Jacek Głowala, Anna Piekarska, Rafał Jurago, Andrzej Tykarski, Krystyna Widecka
Nadciśnienie tętnicze 2012;16(6):338-344.

open access

Vol 16, No 6 (2012)
Prace oryginalne
Published online: 2013-04-12

Abstract

Background The aim of this study was to assess the
therapeutic efficacy and compliance in patients with arterial
hypertension treated with antihypertensive drug
combinations.

Material and methods This open label, non-interventional,
observational, and multicenter study was conducted
by 354 physicians on 4635 patients with arterial hypertension,
in whom treatments with antihypertensive drug combinations
was initiated. The final analyses included medical
records collected from 4218 patients. During an observational
period, two consecutive visits in 3-month intervals
were conducted, in which blood pressure was measured
and self-administrated Morisky-Green questionnaire to
measure medication compliance in hypertensive patients
was performed. Physician’s decision on the choice of treatment
regimen was taken independently of patient inclusion
to the study.

Results At the first visit, only 161 (3.8%) patients had blood
pressure below 140/90 mm Hg, but 4050 (90.2%) patients
were not effectively treated. After applying antihypertensive
drug combinations, target values of blood pressure
were achieved in 1047 (78%) patients. Moreover, an improvement
in patient compliance measured by positive answers
in Morisky-Green questionnaire was also observed.

Conclusions An application of antihypertensive drug combinations
in clinical practice is associated with improvements
in blood pressure control and medication compliance
in arterial hypertension.

Abstract

Background The aim of this study was to assess the
therapeutic efficacy and compliance in patients with arterial
hypertension treated with antihypertensive drug
combinations.

Material and methods This open label, non-interventional,
observational, and multicenter study was conducted
by 354 physicians on 4635 patients with arterial hypertension,
in whom treatments with antihypertensive drug combinations
was initiated. The final analyses included medical
records collected from 4218 patients. During an observational
period, two consecutive visits in 3-month intervals
were conducted, in which blood pressure was measured
and self-administrated Morisky-Green questionnaire to
measure medication compliance in hypertensive patients
was performed. Physician’s decision on the choice of treatment
regimen was taken independently of patient inclusion
to the study.

Results At the first visit, only 161 (3.8%) patients had blood
pressure below 140/90 mm Hg, but 4050 (90.2%) patients
were not effectively treated. After applying antihypertensive
drug combinations, target values of blood pressure
were achieved in 1047 (78%) patients. Moreover, an improvement
in patient compliance measured by positive answers
in Morisky-Green questionnaire was also observed.

Conclusions An application of antihypertensive drug combinations
in clinical practice is associated with improvements
in blood pressure control and medication compliance
in arterial hypertension.
Get Citation

Keywords

complex drugs, hypertension, patient–physician collaboration

About this article
Title

Assessment of the improvement in treatment efficacy and compliance in patients with arterial hypertension treated with antihypertensive drug combinations

Journal

Arterial Hypertension

Issue

Vol 16, No 6 (2012)

Pages

338-344

Published online

2013-04-12

Bibliographic record

Nadciśnienie tętnicze 2012;16(6):338-344.

Keywords

complex drugs
hypertension
patient–physician collaboration

Authors

Joanna Dziwura-Ogonowska
Tomasz Miazgowski
Jacek Głowala
Anna Piekarska
Rafał Jurago
Andrzej Tykarski
Krystyna Widecka

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