Telmisartan in hypertensive treatment — practicalities

Abstract

Blockade of the renin-angiotensin system plays a pivotal role
in the treatment of high blood pressure and prevention of
target organ damage. Telmisartan is an angiotensin II receptor
blocker displaying beneficial unique pharmacologic
properties, metabolic effects, antihypertensive efficacy in
monotherapy and combinations and good tolerance. Clinical
studies confirm that telmisartan improves endothelial function,
insulin sensitivity and lipid profiles, reduces arterial stiffness,
left ventricular hypertrophy and the recurrence of atrial
fibrillation. In addition, telmisartan improves renal function
and has potential beneficial effects on prevention of cerebrovascular
disease. The ONTARGET study has shown that
telmisartan provides similar cardiovascular protection