Pathophysiological and clinical aspects of dopamine

Włodzimierz Januszewicz; Mariola Pęczkowska; Katarzyna Michel-Rowicka; Aleksander Prejbisz; Andrzej Januszewicz

Vol 15, No 1 (2011)

Review paper

Published online: 2011-04-18

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Pathophysiological and clinical aspects of dopamine

Włodzimierz Januszewicz, Mariola Pęczkowska, Katarzyna Michel-Rowicka, Aleksander Prejbisz, Andrzej Januszewicz

Nadciśnienie tętnicze 2011;15(1):37-41.

Vol 15, No 1 (2011)

REVIEV

Published online: 2011-04-18

Abstract

This article summarizes the recent views on the role of dopamine in the pathophysiology of essential hypertension, experimental hypertension and pheochromocytoma. The studies on antiproliferative action of dopamine on VSMC (vascular smooth muscle cell) are mentioned. The authors discuss the potential role of dopamine and its metabolites as a marker of malignant hypertension and paraganglioma, especially in patients with SDHB (succinate dehydrogenase complex subunit B) gene mutations. The clinical implication of specific D1 agonist fenoldopam is also discussed.
Arterial Hypertension 2011, vol. 15, no 1, pages 37–41

Abstract

This article summarizes the recent views on the role of dopamine in the pathophysiology of essential hypertension, experimental hypertension and pheochromocytoma. The studies on antiproliferative action of dopamine on VSMC (vascular smooth muscle cell) are mentioned. The authors discuss the potential role of dopamine and its metabolites as a marker of malignant hypertension and paraganglioma, especially in patients with SDHB (succinate dehydrogenase complex subunit B) gene mutations. The clinical implication of specific D1 agonist fenoldopam is also discussed.
Arterial Hypertension 2011, vol. 15, no 1, pages 37–41

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Keywords

dopamine; dopaminergic receptors; experimental hypertension; malignant hypertension; paraganglioma; fenoldopam

About this article

Title

Pathophysiological and clinical aspects of dopamine

Journal

Arterial Hypertension

Issue

Vol 15, No 1 (2011)

Article type

Review paper

Pages

37-41

Published online

2011-04-18

Page views

598

Article views/downloads

11813

Bibliographic record

Nadciśnienie tętnicze 2011;15(1):37-41.

Keywords

dopamine
dopaminergic receptors
experimental hypertension
malignant hypertension
paraganglioma
fenoldopam

Authors

Włodzimierz Januszewicz
Mariola Pęczkowska
Katarzyna Michel-Rowicka
Aleksander Prejbisz
Andrzej Januszewicz