Vol 15, No 6 (2011)
Review paper
Published online: 2012-02-23
Is there arterial hypertension chronic inflammatory disease?
Nadciśnienie tętnicze 2011;15(6):363-370.
Abstract
Pathogenesis of essential hypertension is complex and, up to now, not well explained. Results of the increasing
number of experimental and clinical studies point to the essential role of inflammation in pathogenesis of
this disease. In patients with hypertension the levels of
CRP, Il-6, tumor necrosis factor and, fibrinogen in blood are usually increased. The increase of CRP is also considered to be the cause of hypertension. In the secondary
forms of hypertension, there is also evidence that not only the high values of blood pressure but also the
increased CRP level are the significant risk factors of cardio-vascular complications. The methods of nonpharmacological
and pharmacological therapy, for
ameliorating of the inflammation which accompanies the hypertension are discussed.
Keywords: hypertensioninflammationlevel of CRP in bloodfree reactive oxygen speciesstatins