open access

Vol 15, No 6 (2011)
REVIEV
Published online: 2012-02-23
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Is there arterial hypertension chronic inflammatory disease?

Jerzy Głuszek, Teresa Kosicka
Nadciśnienie tętnicze 2011;15(6):363-370.

open access

Vol 15, No 6 (2011)
REVIEV
Published online: 2012-02-23

Abstract

Pathogenesis of essential hypertension is complex and, up to now, not well explained. Results of the increasing number of experimental and clinical studies point to the essential role of inflammation in pathogenesis of this disease. In patients with hypertension the levels of CRP, Il-6, tumor necrosis factor and, fibrinogen in blood are usually increased. The increase of CRP is also considered to be the cause of hypertension. In the secondary forms of hypertension, there is also evidence that not only the high values of blood pressure but also the increased CRP level are the significant risk factors of cardio-vascular complications. The methods of nonpharmacological and pharmacological therapy, for ameliorating of the inflammation which accompanies the hypertension are discussed.

Abstract

Pathogenesis of essential hypertension is complex and, up to now, not well explained. Results of the increasing number of experimental and clinical studies point to the essential role of inflammation in pathogenesis of this disease. In patients with hypertension the levels of CRP, Il-6, tumor necrosis factor and, fibrinogen in blood are usually increased. The increase of CRP is also considered to be the cause of hypertension. In the secondary forms of hypertension, there is also evidence that not only the high values of blood pressure but also the increased CRP level are the significant risk factors of cardio-vascular complications. The methods of nonpharmacological and pharmacological therapy, for ameliorating of the inflammation which accompanies the hypertension are discussed.
Get Citation

Keywords

hypertension; inflammation; level of CRP in blood; free reactive oxygen species; statins

About this article
Title

Is there arterial hypertension chronic inflammatory disease?

Journal

Arterial Hypertension

Issue

Vol 15, No 6 (2011)

Pages

363-370

Published online

2012-02-23

Bibliographic record

Nadciśnienie tętnicze 2011;15(6):363-370.

Keywords

hypertension
inflammation
level of CRP in blood
free reactive oxygen species
statins

Authors

Jerzy Głuszek
Teresa Kosicka

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