Is there arterial hypertension chronic inflammatory disease?

Jerzy Głuszek; Teresa Kosicka

Vol 15, No 6 (2011)

Review paper

Published online: 2012-02-23

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Is there arterial hypertension chronic inflammatory disease?

Jerzy Głuszek, Teresa Kosicka

Nadciśnienie tętnicze 2011;15(6):363-370.

Vol 15, No 6 (2011)

REVIEV

Published online: 2012-02-23

Abstract

Pathogenesis of essential hypertension is complex and, up to now, not well explained. Results of the increasing number of experimental and clinical studies point to the essential role of inflammation in pathogenesis of this disease. In patients with hypertension the levels of CRP, Il-6, tumor necrosis factor and, fibrinogen in blood are usually increased. The increase of CRP is also considered to be the cause of hypertension. In the secondary forms of hypertension, there is also evidence that not only the high values of blood pressure but also the increased CRP level are the significant risk factors of cardio-vascular complications. The methods of nonpharmacological and pharmacological therapy, for ameliorating of the inflammation which accompanies the hypertension are discussed.