Intence of ultraviolet irradiation on 25(OH)D3, calcitonin and parathormone concentration in patients with renovascular hypertension

Abstract

Methods In 12 patients with renovascular hypertension and in 10 healthy subjects plasma calcium, inorganic phosphates, 25(OH)-vitamin D3, calcitonin and parathormone concentration were estimated before and 5, and 20 days after start of a 6-days period of ultraviolet irradiation of the skin. Patients with renovascular hypertension did not differ significantly from healthy subjects with respect to all estimated parameters of calcium-phosphate homeostasis.
Results As expected ultraviolet irradiation was followed by a significant increase of plasma 25(OH)D3 concentration. This increase was of similar magnitude both in patients with renovascular hypertension and in healthy subjects. Ultraviolet irradiation did not inf(uence significantly plasma calcitonin and parathormone concentration.
Conlusion Our results suggest, that in patients with renovascular hypertension calciu-phosphate homeostasis is not disturbed both under basal conditions and after ultraviolet irradiation of the skin.