Vol 2, No 3 (1998)
Review paper
Published online: 2000-03-08
Salt Sensitivity of Blood Pressure
Liliana Majkowska
Nadciśnienie tętnicze 1998;2(3):185-191.
Vol 2, No 3 (1998)
REVIEV
Published online: 2000-03-08
Abstract
Epidemiologic data have demonstrated signifcant but weak
relation between salt intake and hypertension. Blood pressure response to alterations in salt intake is heterogenous both
among normotensive and hypertensive subjects. Salt sensitivity can be defined as an increase in blood pressure response
to high sodium intake. This article addresses different established criteria and methodology of sodium sensitivity assessment. Salt sensitivity can be found approximately in 20% of
normotensive and in 50% of hypertensive subjects and is more
common in older, obese, diabetics and blacks. Pathogenesis
of salt sensitivity phenomenon still remains unclear and responsible mechanisms are complex. Salt sensitivity is associated with abnormal hemodynamic response to NaCI loading
and with abnormalities in natriuresis, sympathetic nervous
system activity, hormonal function and cellular ionic transport. Data relating salt sensitivity to these disturbed mechanisms are summarized in the article.
Abstract
Epidemiologic data have demonstrated signifcant but weak
relation between salt intake and hypertension. Blood pressure response to alterations in salt intake is heterogenous both
among normotensive and hypertensive subjects. Salt sensitivity can be defined as an increase in blood pressure response
to high sodium intake. This article addresses different established criteria and methodology of sodium sensitivity assessment. Salt sensitivity can be found approximately in 20% of
normotensive and in 50% of hypertensive subjects and is more
common in older, obese, diabetics and blacks. Pathogenesis
of salt sensitivity phenomenon still remains unclear and responsible mechanisms are complex. Salt sensitivity is associated with abnormal hemodynamic response to NaCI loading
and with abnormalities in natriuresis, sympathetic nervous
system activity, hormonal function and cellular ionic transport. Data relating salt sensitivity to these disturbed mechanisms are summarized in the article.
Keywords
sodium sensitivity; dietary sodium intake; hypertension
Title
Salt Sensitivity of Blood Pressure
Journal
Arterial Hypertension
Issue
Vol 2, No 3 (1998)
Article type
Review paper
Pages
185-191
Published online
2000-03-08
Page views
1272
Bibliographic record
Nadciśnienie tętnicze 1998;2(3):185-191.
Keywords
sodium sensitivity
dietary sodium intake
hypertension
Authors
Liliana Majkowska
About this article