Vol 2, No 3 (1998)
Prace oryginalne
Published online: 2000-03-08
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Indapamide - the Antihypertensive Efficacy and Influence on the Metabolic Profile

Bogdan Wyrzykowski
Nadciśnienie tętnicze 1998;2(3):148-151.
Vol 2, No 3 (1998)
Prace oryginalne
Published online: 2000-03-08

Abstract


Background The aim of presented analysis was to evaluate the antihypertensive efficacy of indapamide and its influence on the blood glucose and lipid profile.
Methods In this Polish open multicenter study indapamide 2,5 mg once daily was given 390 patients with mild to moderate essential hypertension for a period 14 weeks.
Results Pretreatment systolic blood pressure - SBP was 157,6 = 10,6 mmHg, diastolic blood pressure - DBP was 98,1 = 4,9 mmHg (mean = standard deviation). After 14 weeks of treatment SBP was 130,6 = 8,4 mmHg, DBP was 83,1 = 6,2 mmHg (p < 0,001).Total cholesterol and blood glucose were unchanged during indapamide therapy.
Conclusion Our study with indapamide as monotherapy shows that good blood pressure control was obtainded in patients with mild to moderate hypertension. Indapamide does not change metabolic profile.

Abstract


Background The aim of presented analysis was to evaluate the antihypertensive efficacy of indapamide and its influence on the blood glucose and lipid profile.
Methods In this Polish open multicenter study indapamide 2,5 mg once daily was given 390 patients with mild to moderate essential hypertension for a period 14 weeks.
Results Pretreatment systolic blood pressure - SBP was 157,6 = 10,6 mmHg, diastolic blood pressure - DBP was 98,1 = 4,9 mmHg (mean = standard deviation). After 14 weeks of treatment SBP was 130,6 = 8,4 mmHg, DBP was 83,1 = 6,2 mmHg (p < 0,001).Total cholesterol and blood glucose were unchanged during indapamide therapy.
Conclusion Our study with indapamide as monotherapy shows that good blood pressure control was obtainded in patients with mild to moderate hypertension. Indapamide does not change metabolic profile.
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Keywords

indapamide; essential hypertension; total cholesterol; blood glucose

About this article
Title

Indapamide - the Antihypertensive Efficacy and Influence on the Metabolic Profile

Journal

Arterial Hypertension

Issue

Vol 2, No 3 (1998)

Pages

148-151

Published online

2000-03-08

Bibliographic record

Nadciśnienie tętnicze 1998;2(3):148-151.

Keywords

indapamide
essential hypertension
total cholesterol
blood glucose

Authors

Bogdan Wyrzykowski

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