Vol 2, No 3 (1998)
Editorial
Published online: 2000-03-08
Sympathetic Nervous System in Pathophysiology of Hypertension - Role of Adrenergic Inhibitors in Antihypertensive Treatment
Maria Witkowska
Nadciśnienie tętnicze 1998;2(3):124-132.
Vol 2, No 3 (1998)
Artykuły redakcyjne
Published online: 2000-03-08
Abstract
Considerable progress has been made in our understanding
of the role of sympathetic nervous system in the pathogenesis
ofhypertension. Enhanced sympathetic tone is associated with
hemodynamic abnormalities as welt as with the metabolic syndrome of insulin resistance and dyslipidemia. Both hypertension and pressure-unrelated risk for development of atherosclerosis increase the risk of coronary artery disease. Understanding the pathophysiology of hypertension and coronary
risk and their relationship to sympathetic overactivity is helpful in seeking new, more effective antihypertensive drugs.
At present antihypertensive treatment is less efficacious in reducing coronary events in hypertension than would be expected. The different types of antihypertensive are discussed on
the basis of their side-effect profile and favourable or adverse
effects on metabolic syndrome associated with hypertension.
Special attention has been paid on centrally acting I1-imidazoline receptors stimulants
Abstract
Considerable progress has been made in our understanding
of the role of sympathetic nervous system in the pathogenesis
ofhypertension. Enhanced sympathetic tone is associated with
hemodynamic abnormalities as welt as with the metabolic syndrome of insulin resistance and dyslipidemia. Both hypertension and pressure-unrelated risk for development of atherosclerosis increase the risk of coronary artery disease. Understanding the pathophysiology of hypertension and coronary
risk and their relationship to sympathetic overactivity is helpful in seeking new, more effective antihypertensive drugs.
At present antihypertensive treatment is less efficacious in reducing coronary events in hypertension than would be expected. The different types of antihypertensive are discussed on
the basis of their side-effect profile and favourable or adverse
effects on metabolic syndrome associated with hypertension.
Special attention has been paid on centrally acting I1-imidazoline receptors stimulants
Keywords
sympathetic nervous system; hypertension; I1-imidazoline receptor agonist
Title
Sympathetic Nervous System in Pathophysiology of Hypertension - Role of Adrenergic Inhibitors in Antihypertensive Treatment
Journal
Arterial Hypertension
Issue
Vol 2, No 3 (1998)
Article type
Editorial
Pages
124-132
Published online
2000-03-08
Page views
539
Bibliographic record
Nadciśnienie tętnicze 1998;2(3):124-132.
Keywords
sympathetic nervous system
hypertension
I1-imidazoline receptor agonist
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