Vol 3, No 4 (1999)
Review paper
Published online: 2000-03-09
Rare Causes of Hypertension
Andrzej Januszewicz, Cezary Szmigielski, Izabela Łoń
Nadciśnienie tętnicze 1999;3(4):251-256.
Vol 3, No 4 (1999)
REVIEV
Published online: 2000-03-09
Abstract
There are some forms of hypertension which despite rare
occurrence should be included in the diagnosis of hypertension. Some of them have potentially reversible causes.
In some cases early and appropriate treatment allow to avoid
dangerous complications.
Primary reninism is a potentially reversible cause of severe,
secondary hypertension. In the patients with the juxtaglomerular cells tumours increased secretion of renin Leads
to increased aldosterone secretion. The surgical resection
of the tumour is the treatment of choice. Hemangioendothelioma, a tumour secreting endothelin, which is a potent
vasoconstrictor, is a very rare cause of hypertension. Gordon's syndrome is a rare hereditary disorder with hypertension, hyperkaliemia, hyperchloremia and acidemia with
normal glomerular filtration rate. Severe hyperkaliemia is
the most persistent feature of this syndrome.
Glucocorticoid-remediable aldosteronism (GRA) is a hereditary, autosomal dominant disease with hypertension.
The treatment with dexamethasone normalises blood pressure and metabolic disturbances.
Liddle's syndrome, known as pseudohyperaldosteronism is
a rare hereditary, autosomal dominant tubulopathy. Hypertension is caused by an increase in fluid retention and hypervolemia. The treatment of choice is a sodium-depleted
diet combined with amiloride or triamteren.
Abstract
There are some forms of hypertension which despite rare
occurrence should be included in the diagnosis of hypertension. Some of them have potentially reversible causes.
In some cases early and appropriate treatment allow to avoid
dangerous complications.
Primary reninism is a potentially reversible cause of severe,
secondary hypertension. In the patients with the juxtaglomerular cells tumours increased secretion of renin Leads
to increased aldosterone secretion. The surgical resection
of the tumour is the treatment of choice. Hemangioendothelioma, a tumour secreting endothelin, which is a potent
vasoconstrictor, is a very rare cause of hypertension. Gordon's syndrome is a rare hereditary disorder with hypertension, hyperkaliemia, hyperchloremia and acidemia with
normal glomerular filtration rate. Severe hyperkaliemia is
the most persistent feature of this syndrome.
Glucocorticoid-remediable aldosteronism (GRA) is a hereditary, autosomal dominant disease with hypertension.
The treatment with dexamethasone normalises blood pressure and metabolic disturbances.
Liddle's syndrome, known as pseudohyperaldosteronism is
a rare hereditary, autosomal dominant tubulopathy. Hypertension is caused by an increase in fluid retention and hypervolemia. The treatment of choice is a sodium-depleted
diet combined with amiloride or triamteren.
Keywords
hypertension secondary; reninism primary; Gordon' s syndrome; hyperaldosteronism; Liddle' s syndrome
Title
Rare Causes of Hypertension
Journal
Arterial Hypertension
Issue
Vol 3, No 4 (1999)
Article type
Review paper
Pages
251-256
Published online
2000-03-09
Page views
2095
Article views/downloads
1720
Bibliographic record
Nadciśnienie tętnicze 1999;3(4):251-256.
Keywords
hypertension secondary
reninism primary
Gordon's syndrome
hyperaldosteronism
Liddle's syndrome
Authors
Andrzej Januszewicz
Cezary Szmigielski
Izabela Łoń