Vol 4, No 1 (2000)
Review paper
Published online: 2000-03-09
New Insights into the Pathogenesis of Essential Hypertension
Nadciśnienie tętnicze 2000;4(1):53-58.
Abstract
Recent data help to explain the role of genetic and enviromental factors in pathogenesis of hypertension. Mutations in genes involved in tubular transport have been described which may predispose to abnormal sodium metabolism as well as the role of insulin and leptin in hypertension associated with obesity has been suggested.
Keywords: hypertensionsodium metabolismgenetic mutationsleptininsulin