open access

Vol 5, No 1 (2001)
REVIEV
Published online: 2001-01-12
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8. Dopamine and Essential Hypertension — A Possible Link?

Włodzimierz Januszewicz, Dariusz Sitkiewicz, Andrzej Januszewicz, Marek Kabat
Nadciśnienie tętnicze 2001;5(1):61-68.

open access

Vol 5, No 1 (2001)
REVIEV
Published online: 2001-01-12

Abstract

A great progress has been made lately in our knowledge of the role of the peripheral dopaminergic system in the pathogenesis of arterial hypertension. The techniques of molecular biology enabled the better understanding of the structure and function of the dopaminergic receptors. It has been shown that the function of renal dopaminergic system is disturbed in some patients with essential and secondary hypertension. Also the dysfunction of this system was revealed in some types of experimental hypertension. This article summarises recent views on the role of dopamine in the development of hypertension. The clinical implication of specific D1 agonist fenoldopam is also discussed.

Abstract

A great progress has been made lately in our knowledge of the role of the peripheral dopaminergic system in the pathogenesis of arterial hypertension. The techniques of molecular biology enabled the better understanding of the structure and function of the dopaminergic receptors. It has been shown that the function of renal dopaminergic system is disturbed in some patients with essential and secondary hypertension. Also the dysfunction of this system was revealed in some types of experimental hypertension. This article summarises recent views on the role of dopamine in the development of hypertension. The clinical implication of specific D1 agonist fenoldopam is also discussed.
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Keywords

dopamine; dopaminergic receptors; essential hypertension; secondary hypertension; experimental

About this article
Title

8. Dopamine and Essential Hypertension — A Possible Link?

Journal

Arterial Hypertension

Issue

Vol 5, No 1 (2001)

Pages

61-68

Published online

2001-01-12

Bibliographic record

Nadciśnienie tętnicze 2001;5(1):61-68.

Keywords

dopamine
dopaminergic receptors
essential hypertension
secondary hypertension
experimental

Authors

Włodzimierz Januszewicz
Dariusz Sitkiewicz
Andrzej Januszewicz
Marek Kabat

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